1. Constantino MI, Molyneaux L, Limacher-Gisler F, Al-Saeed A, Luo C, Wu T, Twigg SM, Yue DK, Wong J.
Long-term complications and mortality in young-onset diabetes: type 2 diabetes is more hazardous and lethal than type 1 diabetes. Diabetes Care 2013; 36(12): 3863-3869.
https://doi.org/10.2337/dc12-2455CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central2. Zheng Y, He M, Congdon N.
The worldwide epidemic of diabetic retinopathy. Indian J Ophthalmol 2012; 60(5): 428.
https://doi.org/10.4103/0301-4738.100542CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central3. Elahy M, Baindur-Hudson S, Cruzat VF, Newsholme P, Dass CR.
Mechanisms of PEDF-mediated protection against reactive oxygen species damage in diabetic retinopathy and neuropathy. J Endocrinol 2014; 222(3): R129-R139.
https://doi.org/10.1530/JOE-14-0065CrossRef Google Scholar full-text PDF Mendeley PubMed 4. Qing S, Yuan S, Yun C, Hui H, Mao P, Wen F, Ding Y, Liu Q.
Serum miRNA biomarkers serve as a fingerprint for proliferative diabetic retinopathy. Cell Physiol Biochem 2014; 34(5): 1733-1740.
https://doi.org/10.1159/000366374CrossRef Google Scholar full-text PDF Mendeley PubMed 5. Jenkins AJ, Joglekar MV, Hardikar AA, Keech AC, O'Neal DN, Januszewski AS.
Biomarkers in diabetic retinopathy. Rev Diabetic Stud 2015; 12(1-2): 159.
https://doi.org/10.1900/RDS.2015.12.159CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central6. Elamin A, Altahir H, Ismail B, Tuvemo T.
Clinical pattern of childhood type 1 (insulin-dependent) diabetes mellitus in the Sudan. Diabetologia 1992; 35(7): 645-648.
https://doi.org/10.1007/BF00400256CrossRef Google Scholar full-text PDF Mendeley PubMed 7. Buchanan TA, Xiang AH, Page KA. Gestational diabetes mellitus: risks and management during and after pregnancy. Nat Rev Endocrinol 2012; 8(11): 639-649.
https://doi.org/10.1038/nrendo.2012.96CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central8. Grunwald JE, Ying GS, Maguire M, Pistilli M, Daniel E, Alexander J, Whittock-Martin R, Parker C, Mohler E, Lo JC, Townsend R.
Association between retinopathy and cardiovascular disease in patients with chronic kidney disease (from the Chronic Renal Insufficiency Cohort [CRIC] Study). Am J Cardiol 2012; 110(2): 246-253.
https://doi.org/10.1016/j.amjcard.2012.03.014CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central9. Hahr AJ, Molitch ME.
Diabetes, cardiovascular risk and nephropathy. Cardiol Clin 2010; 28(3): 467-475.
https://doi.org/10.1016/j.ccl.2010.04.006CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central
10. Son JW, Jang EH, Kim MK, Kim IT, Roh YJ, Baek KH, Song KH, Yoon KH, Cha BY, Lee KW, Son HY.
Diabetic retinopathy is associated with subclinical atherosclerosis in newly diagnosed type 2 diabetes mellitus. Diabetes Res Clin Pract 2011; 91(2): 253-259.
https://doi.org/10.1016/j.diabres.2010.11.005CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central
11. Zhang X, Saaddine JB, Chou CF, Cotch MF, Cheng YJ, Geiss LS, Gregg EW, Albright AL, Klein BE, Klein R.
Prevalence of diabetic retinopathy in the United States, 2005-2008. Jama 2010; 304(6): 649-656.
https://doi.org/10.1001/jama.2010.1111CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central12. Pusparajah P, Lee LH, Abdul Kadir K.
Molecular markers of diabetic retinopathy: potential screening tool of the future?. Front Physiol 2016; 7: 200.
https://doi.org/10.3389/fphys.2016.00200CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central13. Cunha-Vaz J, Ribeiro L, Lobo C.
Phenotypes and biomarkers of diabetic retinopathy. Prog Retin Eye Res 2014 ; 41: 90-111.
https://doi.org/10.1016/j.preteyeres.2014.03.003CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central
14. Wu L, Fernandez-Loaiza P, Sauma J, Hernandez-Bogantes E, Masis M.
Classification of diabetic retinopathy and diabetic macular edema. World J Diabetes 2013; 4(6): 290.
https://doi.org/10.4239/wjd.v4.i6.290CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central15. Simó R, Hernández C.
Neurodegeneration in the diabetic eye: new insights and therapeutic perspectives. Trends Endocrinol Metab 2014; 25(1): 23-33.
https://doi.org/10.1016/j.tem.2013.09.005CrossRef Google Scholar full-text PDF Mendeley PubMed 16. Cunha-Vaz J, Bernardes R, Lobo C.
Blood-retinal barrier. Eur J Ophthalmol 2011; 21(6_suppl): 3-9.
https://doi.org/10.5301/EJO.2010.6049CrossRef Google Scholar full-text PDF Mendeley PubMed 17. Hammes HP, Lin J, Renner O, Shani M, Lundqvist A, Betsholtz C, Brownlee M, Deutsch U.
Pericytes and the pathogenesis of diabetic retinopathy. Diabetes 2002; 51(10): 3107-3112.
https://doi.org/10.2337/diabetes.51.10.3107CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central
18. S Stem M, W Gardner T.
Neurodegeneration in the pathogenesis of diabetic retinopathy: molecular mechanisms and therapeutic implications. Curr Med Chem 2013; 20(26): 3241-3250.
https://doi.org/10.2174/09298673113209990027CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central19. Holopigian K, Seiple W, Lorenzo M, Carr R.
A comparison of photopic and scotopic electroretinographic changes in early diabetic retinopathy. Invest Ophthalmol Vis Sci 1992; 33(10): 2773-2780. ISSN:
01460404CrossRef Google Scholar full-text PDF Mendeley PubMed 20. Villarroel M, Ciudin A, Hernández C, Simó R.
Neurodegeneration: an early event of diabetic retinopathy. World J Diabetes 2010; 1(2): 57.
https://doi.org/10.4239/wjd.v1.i2.57CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central21. Adams AJ, Bearse Jr MA.
Retinal neuropathy precedes vasculopathy in diabetes: a function‐based opportunity for early treatment intervention?. Clin Exp Optom 2012; 95(3): 256-265.
https://doi.org/10.1111/j.1444-0938.2012.00733.xCrossRef Google Scholar full-text PDF Mendeley PubMed 22. Reis A, Mateus C, Melo P, Figueira J, Cunha-Vaz J, Castelo-Branco M.
Neuroretinal dysfunction with intact blood-retinal barrier and absent vasculopathy in type 1 diabetes. Diabetes 2014; 63(11): 3926-3937.
https://doi.org/10.2337/db13-1673CrossRef Google Scholar full-text PDF Mendeley PubMed 23. Klaassen I, Van Noorden CJ, Schlingemann RO.
Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions. Prog Retin Eye Res 2013; 34: 19-48.
https://doi.org/10.1016/j.preteyeres.2013.02.001CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central
24. Simó-Servat O, Simó R, Hernández C.
Circulating biomarkers of diabetic retinopathy: an overview based on physiopathology. J Diabetes Res 2016; 2016.
https://doi.org/10.1155/2016/5263798CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central25. Aveleira CA, Lin CM, Abcouwer SF, Ambrósio AF, Antonetti DA.
TNF-α signals through PKCζ/NF-κB to alter the tight junction complex and increase retinal endothelial cell permeability. Diabetes 2010; 59(11): 2872-2882.
https://doi.org/10.2337/db09-1606CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central26. Suzuki Y, Nakazawa M, Suzuki K, Yamazaki H, Miyagawa Y.
Expression profiles of cytokines and chemokines in vitreous fluid in diabetic retinopathy and central retinal vein occlusion. Jpn J Ophthalmol 2011; 55(3): 256-263.
https://doi.org/10.1007/s10384-011-0004-8CrossRef Google Scholar full-text PDF Mendeley PubMed 27. Gustavsson C, Agardh E, Bengtsson B, Agardh CD.
TNF-α is an independent serum marker for proliferative retinopathy in type 1 diabetic patients. J Diabetes Complications 2008; 22(5): 309-316.
https://doi.org/10.1016/j.jdiacomp.2007.03.001CrossRef Google Scholar full-text PDF Mendeley PubMed 28. Doganay S, Evereklioglu C, Er H, Türköz Y, Sevinc A, Mehmet N, Şavli H.
Comparison of serum NO, TNF-α, IL-1β, sIL-2R, IL-6 and IL-8 levels with grades of retinopathy in patients with diabetes mellitus. Eye 2002; 16(2): 163-170.
https://doi.org/10.1038/sj.eye.6700095CrossRef Google Scholar full-text PDF Mendeley PubMed 29. Klein BE, Knudtson MD, Tsai MY, Klein R.
The relation of markers of inflammation and endothelial dysfunction to the prevalence and progression of diabetic retinopathy: Wisconsin epidemiologic study of diabetic retinopathy. Arch Ophthalmol 2009; 127(9): 1175-1182.
https://doi.org/10.1001/archophthalmol.2009.172CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central
30. Roy MS, Janal MN, Crosby J, Donnelly R.
Inflammatory biomarkers and progression of diabetic retinopathy in African Americans with type 1 diabetes. Invest Ophthalmol Vis Sci 2013; 54(8): 5471-5480.
https://doi.org/10.1167/iovs.13-12212CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central31. Preciado-Puga MC, Malacara JM, Fajardo-Araujo ME, Wröbel K, Kornhauser-Araujo C, Garay-Sevilla ME.
Markers of the progression of complications in patients with type 2 diabetes: a one-year longitudinal study. Exp Clin Endocrinol Diabetes 2014; 122(08): 484-490.
CrossRef Google Scholar full-text PDF Mendeley PubMed 32. Zorena K, Myśliwska J, Myśliwiec M, Balcerska A, Hak Ł, Lipowski P, Raczyńska K.
Serum TNF-alpha level predicts nonproliferative diabetic retinopathy in children. Mediators Inflamm 2007; 2007.
https://doi.org/10.1155/2007/92196CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central33. Costagliola C, Romano V, De Tollis M, Aceto F, Romano MR, Pedicino C, Semeraro F.
TNF-alpha levels in tears: a novel biomarker to assess the degree of diabetic retinopathy. Mediators Inflamm 2013; 2013.
https://doi.org/10.1155/2013/629529CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central34. Kocabora MS, Telli ME, Fazil K, Erdur SK, Ozsutcu M, Cekic O, Ozbilen KT.
Serum and aqueous concentrations of inflammatory markers in diabetic macular edema. Ocul Immunol Inflamm 2016; 24(5): 549-554.
https://doi.org/10.3109/09273948.2015.1034804CrossRef Google Scholar full-text PDF Mendeley PubMed 35. Patel JI, Saleh GM, Hykin PG, Gregor ZJ, Cree IA.
Concentration of haemodynamic and inflammatory related cytokines in diabetic retinopathy. Eye 2008; 22(2): 223-228.
https://doi.org/10.1038/sj.eye.6702584CrossRef Google Scholar full-text PDF Mendeley PubMed 36. Murugeswari P, Shukla D, Rajendran A, Kim R, Namperumalsamy P, Muthukkaruppan V.
Proinflammatory cytokines and angiogenic and anti-angiogenic factors in vitreous of patients with proliferative diabetic retinopathy and eales’disease. Retina 2008; 28(6): 817-824.
https://doi.org/10.1097/IAE.0b013e31816576d5CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central
37. Shimizu E, Funatsu H, Yamashita H, Yamashita T, Hori S.
Plasma level of interleukin-6 is an indicator for predicting diabetic macular edema. Jpn J Ophthalmol 2002; 46(1): 78-83.
https://doi.org/10.1016/S0021-5155(01)00452-XCrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central
38. Nguyen TT, Alibrahim E, Islam FA, Klein R, Klein BE, Cotch MF, Shea S, Wong TY.
Inflammatory, hemostatic, and other novel biomarkers for diabetic retinopathy: the multi-ethnic study of atherosclerosis. Diabetes Care 2009; 32(9): 1704-1709.
https://doi.org/10.2337/dc09-0102CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central39. Le DS, Miles R, Savage PJ, Cornell E, Tracy RP, Knowler WC, Krakoff J.
The association of plasma fibrinogen concentration with diabetic microvascular complications in young adults with early-onset of type 2 diabetes. Diabetes Res Clin Pract 2008; 82(3): 317-323.
https://doi.org/10.1016/j.diabres.2008.08.019CrossRef Google Scholar full-text PDF Mendeley PubMed 40. Schram MT, Chaturvedi N, Schalkwijk CG, Fuller JH, Stehouwer CD.
Markers of inflammation are cross-sectionally associated with microvascular complications and cardiovascular disease in type 1 diabetes—the EURODIAB Prospective Complications Study. Diabetologia 2005; 48(2): 370-378.
https://doi.org/10.1007/s00125-004-1628-8CrossRef Google Scholar full-text PDF Mendeley PubMed 41. Christou GA, Tselepis AD, Kiortsis DN.
The metabolic role of retinol binding protein 4: an update.https://doi.org/10.1055/s-0031-1295491CrossRef Google Scholar full-text PDF Mendeley PubMed 42. Farjo KM, Farjo RA, Halsey S, Moiseyev G, Ma JX.
Retinol-binding protein 4 induces inflammation in human endothelial cells by an NADPH oxidase-and nuclear factor kappa B-dependent and retinol-independent mechanism. Mol Cell Biol 2012; 32(24): 5103.
https://doi.org/10.1128/mcb.00820-12CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central43. Du M, Otalora L, Martin AA, Moiseyev G, Vanlandingham P, Wang Q, Farjo R, Yeganeh A, Quiambao A, Farjo KM.
Transgenic mice overexpressing serum retinol-binding protein develop progressive retinal degeneration through a retinoid-independent mechanism. Mol Cell Biol 2015; 35(16): 2771.
https://doi.org/10.1128/mcb.00181-15CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central44. Takebayashi K, Suetsugu M, Wakabayashi S, Aso Y, Inukai T.
Retinol binding protein-4 levels and clinical features of type 2 diabetes patients. J Clin endocrinol Metab 2007; 92(7): 2712-2719.
https://doi.org/10.1210/jc.2006-1249CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central
45. Cabre A, Lazaro I, Girona J, Manzanares J, Marimon F, Plana N, Heras M, Masana L.
Retinol‐binding protein 4 as a plasma biomarker of renal dysfunction and cardiovascular disease in type 2 diabetes. J Int Med 2007; 262(4): 496-503.
https://doi.org/10.1111/j.1365-2796.2007.01849.xCrossRef Google Scholar full-text PDF Mendeley PubMed 46. Bringmann A, Pannicke T, Grosche J, Francke M, Wiedemann P, Skatchkov SN, Osborne NN, Reichenbach A.
Müller cells in the healthy and diseased retina. Prog Retin Eye Res 2006; 25(4): 397-424.
https://doi.org/10.1016/j.preteyeres.2006.05.003CrossRef Google Scholar full-text PDF Mendeley PubMed 47. Hidalgo‐Lanussa O, Baez‐Jurado E, Echeverria V, Ashraf GM, Sahebkar A, Garcia‐Segura LM, Melcangi RC, Barreto GE.
Lipotoxicity, neuroinflammation, glial cells and oestrogenic compounds. J Neuroendocrinol 2020; 32(1): e12776.
https://doi.org/10.1111/jne.12776CrossRef Google Scholar full-text PDF Mendeley PubMed 48. Bringmann A, Wiedemann P.
Müller glial cells in retinal disease. Ophthalmologica 2012; 227(1): 1-9.
https://doi.org/10.1159/000328979CrossRef Google Scholar full-text PDF Mendeley PubMed 49. Gerhardinger C, Costa MB, Coulombe MC, Toth I, Hoehn T, Grosu P.
Expression of acute-phase response proteins in retinal Muller cells in diabetes. Invest Ophthalmol Vis Sci 2005; 46(1): 349-357.
https://doi.org/10.1167/iovs.04-0860CrossRef Google Scholar full-text PDF Mendeley PubMed 50. Barber AJ, Antonetti DA, Gardner TW.
Altered expression of retinal occludin and glial fibrillary acidic protein in experimental diabetes. Invest Ophthalmol Vis Sci 2000; 41(11): 3561-3568. ISSN:
01460404CrossRef Google Scholar full-text PDF Mendeley PubMed 51. Sarthy V.
Focus on molecules: glial fibrillary acidic protein (GFAP). Exp Eye Res 2006; 84(3): 381-382.
https://doi.org/10.1016/j.exer.2005.12.014CrossRef Google Scholar full-text PDF Mendeley PubMed 52. Carrasco E, Hernández C, Miralles A, Huguet P, Farrés J, Simó R.
Lower somatostatin expression is an early event in diabetic retinopathy and is associated with retinal neurodegeneration. Diabetes Care 2007; 30(11): 2902-2908.
https://doi.org/10.2337/dc07-0332CrossRef Google Scholar full-text PDF Mendeley PubMed 53. Vujosevic S, Micera A, Bini S, Berton M, Esposito G, Midena E.
Aqueous humor biomarkers of Müller cell activation in diabetic eyes. Invest Ophthalmol Vis Sci 2015; 56(6): 3913-3918.
https://doi.org/10.1167/iovs.15-16554CrossRef Google Scholar full-text PDF Mendeley PubMed 54. Iandiev I, Pannicke T, Reichenbach A, Wiedemann P, Bringmann A.
Diabetes alters the localization of glial aquaporins in rat retina. Neurosci Lett 2007; 421(2): 132-136.
https://doi.org/10.1016/j.neulet.2007.04.076CrossRef Google Scholar full-text PDF Mendeley PubMed 55. Iandiev I, Pannicke T, Hollborn M, Wiedemann P, Reichenbach A, Grimm C, Remé CE, Bringmann A.
Localization of glial aquaporin-4 and Kir4. 1 in the light-injured murine retina. Neurosci Lett 2008; 434(3): 317-321.
https://doi.org/10.1016/j.neulet.2008.02.026CrossRef Google Scholar full-text PDF Mendeley PubMed 56. Zhang Y, Xu G, Ling Q, Da C.
Expression of aquaporin 4 and Kir4. 1 in diabetic rat retina: treatment with minocycline. J Int Med Res 2011; 39(2): 464-479.
https://doi.org/10.1177/147323001103900214CrossRef Google Scholar full-text PDF Mendeley PubMed 57. Cui B, Sun JH, Xiang FF, Liu L, Li WJ.
Aquaporin 4 knockdown exacerbates streptozotocin-induced diabetic retinopathy through aggravating inflammatory response. Exp Eye Res 2012; 98: 37-43.
https://doi.org/10.1016/j.exer.2012.02.013CrossRef Google Scholar full-text PDF Mendeley PubMed 58. Vujosevic S, Midena E.
Retinal layers changes in human preclinical and early clinical diabetic retinopathy support early retinal neuronal and Müller cells alterations. J Diabetes Res 2013; 2013.
https://doi.org/10.1155/2013/905058CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central59. McGeer PL, McGeer EG.
The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases. Brain Res Rev 1995; 21(2): 195-218.
https://doi.org/10.1016/0165-0173(95)00011-9CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central
60. Lynch MA.
The multifaceted profile of activated microglia. Mol Neurobiol 2009; 40(2): 139-156.
https://doi.org/10.1007/s12035-009-8077-9CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central
61. Vujosevic S, Bini S, Midena G, Berton M, Pilotto E, Midena E.
Hyperreflective intraretinal spots in diabetics without and with nonproliferative diabetic retinopathy: an in vivo study using spectral domain OCT. J Diabetes Res 2013; 2013.
https://doi.org/10.1155/2013/491835CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central62. Zeng HY, Green WR, Tso MO.
Microglial activation in human diabetic retinopathy. Arch Ophthalmol 2008; 126(2): 227-232.
CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central
63. Vujosevic S, Bini S, Torresin T, Berton M, Midena G, Parrozzani R, Martini F, Pucci P, Daniele AR, Cavarzeran F, Midena E.
Hyperreflective retinal spots in normal and diabetic eyes: B-scan and en face spectral domain optical coherence tomography evaluation. Retina 2017; 37(6): 1092-1103.
https://doi.org/10.1097/IAE.0000000000001304CrossRef Google Scholar full-text PDF Mendeley PubMed 64. Hanisch UK, Kettenmann H.
Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci 2007; 10(11): 1387-1394.
https://doi.org/10.1038/nn1997CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central
65. Vujosevic S, Micera A, Bini S, Berton M, Esposito G, Midena E.
Proteome analysis of retinal glia cells‐related inflammatory cytokines in the aqueous humour of diabetic patients. Acta Ophthalmol 2016; 94(1): 56-64.
https://doi.org/10.1111/aos.12812CrossRef Google Scholar full-text PDF Mendeley PubMed 66. Funatsu H, Yamashita H, Noma H, Mimura T, Yamashita T, Hori S. Increased levels of vascular endothelial growth factor and interleukin-6 in the aqueous humor of diabetics with macular edema. Am J Ophthalmol 2002; 133(1): 70-77.
https://doi.org/10.1016/S0002-9394(01)01269-7CrossRef Google Scholar full-text PDF Mendeley PubMed 67. Cheung CM, Vania M, Ang M, Chee SP, Li J.
Comparison of aqueous humor cytokine and chemokine levels in diabetic patients with and without retinopathy. Mol Vis 2012; 18: 830.
CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central68. Antunica AG, Karaman K, Znaor L, Sapunar A, Buško V, Puzović V.
IL-12 concentrations in the aqueous humor and serum of diabetic retinopathy patients. Graefe's Arch Clin Exp Ophthalmol 2012; 250(6): 815-821.
https://doi.org/10.1007/s00417-011-1905-4CrossRef Google Scholar full-text PDF Mendeley PubMed 69. Jonas JB, Jonas RA, Neumaier M, Findeisen P.
Cytokine concentration in aqueous humor of eyes with diabetic macular edema. Retina 2012; 32(10): 2150-2157.
https://doi.org/10.1097/IAE.0b013e3182576d07CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central
70. Hernandez C, Segura RM, Fonollosa A, Carrasco E, Francisco G, Simo R.
Interleukin‐8, monocyte chemoattractant protein‐1 and IL‐10 in the vitreous fluid of patients with proliferative diabetic retinopathy. Diabetic Med 2005; 22(6): 719-722.
https://doi.org/10.1111/j.1464-5491.2005.01538.xCrossRef Google Scholar full-text PDF Mendeley PubMed 71. Hernández C, Garcia-Ramírez M, Simó R.
Overexpression of hemopexin in the diabetic eye: a new pathogenic candidate for diabetic macular edema. Diabetes Care 2013; 36(9): 2815-2821.
https://doi.org/10.2337/dc12-2634CrossRef Google Scholar full-text PDF Mendeley PubMed PubMed Central72. Cheung PK, Klok PA, Baller JF, Bakker WW. Induction of experimental proteinuria in vivo following infusion of human plasma hemopexin. Kidney Int 2000; 57(4): 1512-1520.
https://doi.org/10.1046/j.1523-1755.2000.00996.xCrossRef Google Scholar full-text PDF
Mendeley PubMed 73. Myśliwiec M, Balcerska A, Zorena K, Myśliwska J, Lipowski P, Raczyńska K.
The role of vascular endothelial growth factor, tumor necrosis factor alpha and interleukin-6 in pathogenesis of diabetic retinopathy. Diabetes Res Clin Pract 2008; 79(1): 141-146.
https://doi.org/10.1016/j.diabres.2007.07.011CrossRef Google Scholar full-text PDF Mendeley PubMed 74. Funatsu H, Yamashita H, Sakata K, Noma H, Mimura T, Suzuki M, Eguchi S, Hori S.
Vitreous levels of vascular endothelial growth factor and intercellular adhesion molecule 1 are related to diabetic macular edema. Ophthalmology 2005; 112(5): 806-816.
https://doi.org/10.1016/j.ophtha.2004.11.045CrossRef Google Scholar full-text PDF Mendeley PubMed 75. Kapojos JJ, Van Den Berg A, Van Goor H, Te Loo MW, Poelstra K, Borghuis T, Bakker WW. Production of hemopexin by TNF-α stimulated human mesangial cells. Kidney Int. 2003; 63(5): 1681-1686.
https://doi.org/10.1046/j.1523-1755.2003.00907.xCrossRef Google Scholar full-text PDF Mendeley PubMed 76. Chan AK, Chiu RW, Lo YD.
Cell-free nucleic acids in plasma, serum and urine: a new tool in molecular diagnosis. Ann Clin Biochem 2003; 40(2): 122-130.
CrossRef Google Scholar full-text PDF Mendeley PubMed 77. Hamaoui K, Butt A, Powrie J, Swaminathan R.
Concentration of circulating rhodopsin mRNA in diabetic retinopathy. Clin Chem 2004; 50(11): 2152-2155.
https://doi.org/10.1373/clinchem.2004.037168CrossRef Google Scholar full-text PDF Mendeley PubMed 78. Hargrave PA.
Rhodopsin structure, function, and topography the Friedenwald lecture. Invest Ophthalmol Vis Sci 2001; 42(1): 3-9. ISSN:
01460404CrossRef Google Scholar full-text PDF Mendeley PubMed 79. Butt A, Ahmad MS, Powrie J, Swaminathan R.
Assessment of diabetic retinopathy by measuring retina-specific mRNA in blood. Expert Opin Biol Ther 2012; 12: S79-S84.
https://doi.org/10.1517/14712598.2012.688947CrossRef Google Scholar full-text PDF Mendeley PubMed 80. Shalchi Z, Sandhu HS, Butt AN, Smith S, Powrie J, Swaminathan R.
Retina‐Specific mRNA in the Assessment of Diabetic Retinopathy. Ann N.Y. Acad Sci 2008; 1137(1): 253-257.
https://doi.org/10.1196/annals.1448.008CrossRef Google Scholar full-text PDF Mendeley PubMed 81. Ambros V.
The functions of animal microRNAs. Nature. 2004; 431(7006): 350-355.
https://doi.org/10.1038/nature02871CrossRef Google Scholar full-text PDF Mendeley PubMed 82. Bartel DP.
MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116(2): 281-297.
https://doi.org/10.1016/S0092-8674(04)00045-5CrossRef Google Scholar full-text PDF Mendeley PubMed 83. Bartel DP.
MicroRNAs: target recognition and regulatory functions. Cell 2009; 136(2): 215-233.
https://doi.org/10.1016/j.cell.2009.01.002CrossRef Google Scholar full-text PDF Mendeley PubMed 84. Rajasekar P, O’Neill CL, Eeles L, Stitt AW, Medina RJ.
Epigenetic changes in endothelial progenitors as a possible cellular basis for glycemic memory in diabetic vascular complications. J Diabetes Res 2015; 2015.
https://doi.org/10.1155/2015/436879CrossRef Google Scholar full-text PDF Mendeley PubMed 85. Feng B, Chen S, McArthur K, Wu Y, Sen S, Ding Q, Feldman RD, Chakrabarti S.
miR-146a–mediated extracellular matrix protein production in chronic diabetes complications. Diabetes 2011; 60(11): 2975-2984.
https://doi.org/10.2337/db11-0478