Abstract
Pain is a frequent and disabling symptom among multiple sclerosis (MS) and it is estimated to occur in 55% to 65% of patients. The mechanism of pain in MS has not yet been defined, because it can result from somatic, visceral, emotional, or neurologic impairment. The importance of this classification is related to different medical approaches to treat the pain in MS patients. In the management of symptomatic pain, new therapeutic strategies are now available to represent a great opportunity improving the quality of life. The availability of newer drugs for symptomatic treatment of pain in MS indicates a need to pay attention to this problem.
Keywords: Psychogenic Pain, Trigeminal neuralgia, Carbamazepine, Phenytoin, Lamotrigine, Tricyclic antidepressants, Cannabinoids
Current Clinical Pharmacology
Title: Drugs Treatment of Pain in Multiple Sclerosis
Volume: 2 Issue: 3
Author(s): Antonio Siniscalchi, Luca Gallelli and Giovambattista De Sarro
Affiliation:
Keywords: Psychogenic Pain, Trigeminal neuralgia, Carbamazepine, Phenytoin, Lamotrigine, Tricyclic antidepressants, Cannabinoids
Abstract: Pain is a frequent and disabling symptom among multiple sclerosis (MS) and it is estimated to occur in 55% to 65% of patients. The mechanism of pain in MS has not yet been defined, because it can result from somatic, visceral, emotional, or neurologic impairment. The importance of this classification is related to different medical approaches to treat the pain in MS patients. In the management of symptomatic pain, new therapeutic strategies are now available to represent a great opportunity improving the quality of life. The availability of newer drugs for symptomatic treatment of pain in MS indicates a need to pay attention to this problem.
Export Options
About this article
Cite this article as:
Siniscalchi Antonio, Gallelli Luca and De Sarro Giovambattista, Drugs Treatment of Pain in Multiple Sclerosis, Current Clinical Pharmacology 2007; 2 (3) . https://dx.doi.org/10.2174/157488407781668785
DOI https://dx.doi.org/10.2174/157488407781668785 |
Print ISSN 1574-8847 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3938 |
Related Articles
-
Decreasing Arterial Aging by Controlling Blood Pressure Levels and Hypertension: A Step Forward
Current Vascular Pharmacology Venom-Sweet-Venom: N-Linked Glycosylation in Snake Venom Toxins
Protein & Peptide Letters Brain Protection and Cognitive Function: Cocoa Flavonoids as Nutraceuticals
Current Pharmaceutical Design Endocannabinoids and their Involvement in the Neurovascular System
Current Neurovascular Research Paclitaxel Formulations: Challenges and Novel Delivery Options
Current Drug Delivery Cathinone Neurotoxicity (“The “3Ms”)
Current Neuropharmacology The Therapeutic Potential and Usage Patterns of Cannabinoids in People with Spinal Cord Injuries: A Systematic Review
Current Neuropharmacology Docking, Synthesis and Anti-Diabetic Activity of Novel Sulfonylhydrazone Derivatives Designed as PPAR-Gamma Agonists
Current Topics in Medicinal Chemistry Therapeutic Macromolecular Iron Chelators
Current Medicinal Chemistry Life Threatening and Fatal Contrast Media Reactions: Pathomechanisms, Diagnosis, Prevention and Drug Management
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry The Relevance of Drug Volume of Distribution in Antibiotic Dosing
Current Pharmaceutical Biotechnology Pharmacological Targets for the Inhibition of Neurogenic Inflammation
Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents Goal Directed Fluid Therapy
Current Pharmaceutical Design Possible Therapies of Septic Shock: Based on Animal Studies and Clinical Trials
Current Pharmaceutical Design Opioids and Mechanical Ventilation
Current Drug Targets The Effect of Anti-B-cell Therapy on the Development of Atherosclerosis in Patients with Rheumatoid Arthritis
Current Pharmaceutical Design Molecular Mechanisms of Biological Activity of Oleanolic Acid - A Source of Inspiration for A New Drugs Design
Mini-Reviews in Organic Chemistry Current Prevention and Treatment of Postoperative Nausea and Vomiting after Gynecological Laparoscopic Surgery
Current Drug Therapy Gender Differences in Hemodynamic Regulation and Cardiovascular Adaptations to Dynamic Exercise
Current Cardiology Reviews Nimodipine Reappraised: An Old Drug With a Future
Current Neuropharmacology