Abstract
Concurrent infection with hepatitis B virus (HBV) and hepatitis C virus (HCV) in patients positive for human immunodeficiency virus (HIV) is relatively common. The treatment of co-infected individuals is rather complex because the anti-viral therapy may be associated with drug-resistance, hepatotoxicity and lack of response. Herein, we present a summary of the available compounds and the recent recommendations concerning the therapeutic management of HIV/HBV and HIV/HCV co-infections.
Keywords: HIV, HBV, HCV, co-infection, treatment, drugs, hepatitis B, hepatocellular carcinoma, adefovir, lamivudine, entecavir
Mini-Reviews in Medicinal Chemistry
Title:Recent Advances in the Treatment of HIV/HBV and HIV/HCV Co-Infection
Volume: 12 Issue: 9
Author(s): A. Masgala, S. Bonovas and G. K. Nikolopoulos
Affiliation:
Keywords: HIV, HBV, HCV, co-infection, treatment, drugs, hepatitis B, hepatocellular carcinoma, adefovir, lamivudine, entecavir
Abstract: Concurrent infection with hepatitis B virus (HBV) and hepatitis C virus (HCV) in patients positive for human immunodeficiency virus (HIV) is relatively common. The treatment of co-infected individuals is rather complex because the anti-viral therapy may be associated with drug-resistance, hepatotoxicity and lack of response. Herein, we present a summary of the available compounds and the recent recommendations concerning the therapeutic management of HIV/HBV and HIV/HCV co-infections.
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Cite this article as:
Masgala A., Bonovas S. and K. Nikolopoulos G., Recent Advances in the Treatment of HIV/HBV and HIV/HCV Co-Infection, Mini-Reviews in Medicinal Chemistry 2012; 12 (9) . https://dx.doi.org/10.2174/138955712800959062
DOI https://dx.doi.org/10.2174/138955712800959062 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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