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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Recent Advances in the Treatment of HIV/HBV and HIV/HCV Co-Infection

Author(s): A. Masgala, S. Bonovas and G. K. Nikolopoulos

Volume 12, Issue 9, 2012

Page: [890 - 904] Pages: 15

DOI: 10.2174/138955712800959062

Price: $65

Abstract

Concurrent infection with hepatitis B virus (HBV) and hepatitis C virus (HCV) in patients positive for human immunodeficiency virus (HIV) is relatively common. The treatment of co-infected individuals is rather complex because the anti-viral therapy may be associated with drug-resistance, hepatotoxicity and lack of response. Herein, we present a summary of the available compounds and the recent recommendations concerning the therapeutic management of HIV/HBV and HIV/HCV co-infections.

Keywords: HIV, HBV, HCV, co-infection, treatment, drugs, hepatitis B, hepatocellular carcinoma, adefovir, lamivudine, entecavir

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