Development of Primary Thyroid Lymphoma during an Ultrasonographic Follow-up of Hashimoto's Thyroiditis: A Report of 9 Cases

Tetsuya Mizokami; Katsuhiko Hamada; Tetsushi Maruta; Kiichiro Higashi; Hiroto Yamashita; Yasushi Noguchi; Hitoshi Noguchi; Junichi Tajiri

doi:10.2169/internalmedicine.55.5428

CASE REPORTS

Development of Primary Thyroid Lymphoma during an Ultrasonographic Follow-up of Hashimoto's Thyroiditis: A Report of 9 Cases

Tetsuya Mizokami, Katsuhiko Hamada, Tetsushi Maruta, Kiichiro Higashi, Hiroto Yamashita, Yasushi Noguchi, Hitoshi Noguchi, Junichi Tajiri

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Keywords: thyroid lymphoma, MALT lymphoma, Hashimoto's thyroiditis, ultrasonography

JOURNAL OPEN ACCESS

2016 Volume 55 Issue 8 Pages 943-948

DOI https://doi.org/10.2169/internalmedicine.55.5428

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Abstract

We herein experienced 9 patients with primary thyroid lymphoma that developed during 3-18 years of ultrasonographic follow-up of Hashimoto's thyroiditis. All nine patients had localized mucosa-associated lymphoid tissue (MALT) lymphoma. Two patients had diffuse type, one had mixed type, and six had nodular type according to the ultrasonographic classification. A clearly enlarging goiter was observed before the diagnosis of lymphoma in 3 patients. An enlarging goiter was not apparent in the remaining 6 patients with nodular type lymphoma, however, the emergence or enlargement of a hypoechoic nodular lesion was observed. Thyroid MALT lymphoma may be diagnosed early by an ultrasonographic follow-up of Hashimoto's thyroiditis.

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