Infective Endocarditis Associated with Mitral Valve Prolapse in a Patient with Klinefelter Syndrome

Yasushi Ueki; Atsushi Izawa; Souichiro Ebisawa; Hirohiko Motoki; Yusuke Miyashita; Takeshi Tomita; Jun Koyama; Tamaki Takano; Jun Amano; Uichi Ikeda

doi:10.2169/internalmedicine.53.1748

CASE REPORTS

Infective Endocarditis Associated with Mitral Valve Prolapse in a Patient with Klinefelter Syndrome

Yasushi Ueki, Atsushi Izawa, Souichiro Ebisawa, Hirohiko Motoki, Yusuke Miyashita, Takeshi Tomita, Jun Koyama, Tamaki Takano, Jun Amano, Uichi Ikeda

Author information

Yasushi Ueki
Department of Cardiovascular Medicine, Shinshu University School of Medicine, Japan
Atsushi Izawa
Department of Cardiovascular Medicine, Shinshu University School of Medicine, Japan
Souichiro Ebisawa
Department of Cardiovascular Medicine, Shinshu University School of Medicine, Japan
Hirohiko Motoki
Department of Cardiovascular Medicine, Shinshu University School of Medicine, Japan
Yusuke Miyashita
Department of Cardiovascular Medicine, Shinshu University School of Medicine, Japan
Takeshi Tomita
Department of Cardiovascular Medicine, Shinshu University School of Medicine, Japan
Jun Koyama
Department of Cardiovascular Medicine, Shinshu University School of Medicine, Japan
Tamaki Takano
Department of Cardiovascular Surgery, Shinshu University School of Medicine, Japan
Jun Amano
Department of Cardiovascular Surgery, Shinshu University School of Medicine, Japan
Uichi Ikeda
Department of Cardiovascular Medicine, Shinshu University School of Medicine, Japan

Keywords: infective endocarditis, mitral valve prolapse, Klinefelter syndrome, echocardiography

JOURNAL OPEN ACCESS

2014 Volume 53 Issue 9 Pages 969-972

DOI https://doi.org/10.2169/internalmedicine.53.1748

Details

Abstract

We herein report a case of infective endocarditis associated with mitral valve prolapse (MVP) in a 34-year-old man with Klinefelter syndrome. The patient was admitted with a fever and headache that had persisted for three weeks. Repeated blood cultures showed growth of Streptococcus oralis. Echocardiography demonstrated severe mitral regurgitation with a large vegetation attached to the prolapsed anterior leaflet. Surgical plasty of the mitral valve was performed because the vegetation measured over 10 mm in diameter and there was a risk of recurrence of embolic complications. This case demonstrates the link between MVP and Klinefelter syndrome and highlights the importance of performing cardiovascular screening and preventing endocarditis.

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