Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Calcium-Alkali Syndrome-Like Symptoms Manifested by Daily Alphacalcidol and Thiazide
Fumie Satoh, Tomokazu Okado, Mari Iwamoto, Wataru Akita, Mai Wakabayashi, Akihito Ohta, Eisei Sohara, Yumi Noda, Tatemitsu Rai, Shinichi Uchida, Sei Sasaki
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Keywords: calcium-alkali syndrome, hypercalcemia, metabolic alkalosis, alphacalcidol, thiazides, milk-alkali syndrome
JOURNAL OPEN ACCESS

2010 Volume 49 Issue 9 Pages 837-840

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Abstract

A 73-year-old man was admitted with complaints of a 2-month history of generalized weakness and numbness. Laboratory examination revealed hypercalcemia, metabolic alkalosis, and kidney injury, similar to the traditional milk-alkali syndrome. The clinical history and the response to therapy indicated that alphacalcidol and thiazide taken daily were the cause. Recently, it has been recommended the term "milk-alkali syndrome" be replaced by "calcium-alkali syndrome", which broadens the definition of the condition. This case suggests that the calcium-alkali syndrome can occur without calcium and alkali, but rather with alphacalcidol and a thiazide diuretic.

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© 2010 by The Japanese Society of Internal Medicine
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