Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Primary Cholesterol Hepatolithiasis Associated with Cholangiocellular Carcinoma: A Case Report and Literature Review
Hiroshi Kawakami, Masaki Kuwatani, Manabu Onodera, Satoshi Hirano, Satoshi Kondo, Yoshitsugu Nakanishi, Tomoo Itoh, Masahiro Asaka
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Keywords: hepatolithiasis, intrahepatic stones, intrahepatic calculi, cholesterol stone, cholesterol hepatolithiasis, cholangiocellular carcinoma
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2007 Volume 46 Issue 15 Pages 1191-1196

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Abstract

Hepatolithiasis associated with cholangiocellular carcinoma is occasionally a calcium bilirubinate stone. Primary cholesterol hepatolithiasis associated with cholangiocellular carcinoma is rare; only 6 cases have been reported in the literature. A 55-year-old man was admitted to our hospital because of an elevated level of carbohydrate antigen 19-9. Various imaging studies demonstrated a mass in the segment VII of the liver. The patient underwent a curative surgical operation. Histopathological examination revealed that it was cholangiocellular carcinoma located in the periphery of the liver. A cholesterol stone was present, encircled by the cholangiocellular carcinoma. Minor inflammatory changes were observed around the stone.

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© 2007 by The Japanese Society of Internal Medicine
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