Pleural Involvement of Dialysis-Related Amyloidosis

Masaru SUZUKI; Tomoko BETSUYAKU; Tetsuya KOJIMA; Hiroshi SAITO; Yoichi NISHIURA; Yuichiro FUKASAWA; Masaharu NISHIMURA; Yoshikazu KAWAKAMI

doi:10.2169/internalmedicine.44.628

CASE REPORTS

Pleural Involvement of Dialysis-Related Amyloidosis

Masaru SUZUKI, Tomoko BETSUYAKU, Tetsuya KOJIMA, Hiroshi SAITO, Yoichi NISHIURA, Yuichiro FUKASAWA, Masaharu NISHIMURA, Yoshikazu KAWAKAMI

Author information

Masaru SUZUKI
Department of Respiratory Medicine, Kohnan Hospital, Federation of National Public Service Personnel Mutual Aid Associations, Sapporo
First Department of Medicine, Hokkaido University School of Medicine, Sapporo
Tomoko BETSUYAKU
First Department of Medicine, Hokkaido University School of Medicine, Sapporo
Tetsuya KOJIMA
Department of Respiratory Medicine, Kohnan Hospital, Federation of National Public Service Personnel Mutual Aid Associations, Sapporo
Hiroshi SAITO
Department of Respiratory Medicine, Kohnan Hospital, Federation of National Public Service Personnel Mutual Aid Associations, Sapporo
Yoichi NISHIURA
Department of Respiratory Medicine, Kohnan Hospital, Federation of National Public Service Personnel Mutual Aid Associations, Sapporo
Yuichiro FUKASAWA
Department of Clinical Laboratory and Anatomical Pathology, Kohnan Hospital, Federation of National Public Service Personnel Mutual Aid Associations, Sapporo
Masaharu NISHIMURA
First Department of Medicine, Hokkaido University School of Medicine, Sapporo
Yoshikazu KAWAKAMI
Department of Respiratory Medicine, Kohnan Hospital, Federation of National Public Service Personnel Mutual Aid Associations, Sapporo

Keywords: dialysis-related amyloidosis, β₂-microglobulin, pleura, pleural amyloidosis, pleural effusion, thoracoscopy

JOURNAL OPEN ACCESS

2005 Volume 44 Issue 6 Pages 628-631

DOI https://doi.org/10.2169/internalmedicine.44.628

Details

Abstract

Two cases of pleural involvement of dialysis-related amyloidosis (DRA) with pleural effusion are presented. DRA is one of the most important complications in long-term dialysis patients and β₂-microglobulin is the principal protein component of DRA, but pleural deposition of β₂-microglobulin amyloid has not yet been reported. To the best of the authors’ knowledge, this is the first case report of pleural involvement of DRA presenting with pleural effusion. This case study suggests that pleural involvement of DRA should be considered when exudative pleural effusion is observed in patients undergoing long-term dialysis.

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