Takotsubo (Ampulla-shaped) Cardiomyopathy Associated with Microscopic Polyangiitis

Takeo SATO; Kiyofumi HAGIWARA; Aya NISHIKIDO; Shingo MIYAMOTO; Kota KOMIYAMA; Hiroaki MATSUNO; Hideji HASHIDA; Naoshi KOBAYAKAWA; Osamu AKIYAMA

doi:10.2169/internalmedicine.44.251

CASE REPORTS

Takotsubo (Ampulla-shaped) Cardiomyopathy Associated with Microscopic Polyangiitis

Takeo SATO, Kiyofumi HAGIWARA, Aya NISHIKIDO, Shingo MIYAMOTO, Kota KOMIYAMA, Hiroaki MATSUNO, Hideji HASHIDA, Naoshi KOBAYAKAWA, Osamu AKIYAMA

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Keywords: inverted T wave, microscopic polyangiitis, myeloperoxidase-antineutrophil cytoplasmic antibody, myocardial injury, takotsubo cardiomyopathy, ventricular dysfunction

JOURNAL OPEN ACCESS

2005 Volume 44 Issue 3 Pages 251-255

DOI https://doi.org/10.2169/internalmedicine.44.251

Details

Abstract

Recently, a cardiac disorder characterized by ballooning and hypokinesis at the apex has been described as takotsubo (ampulla-shaped) cardiomyopathy. We encountered a patient with a rare case of takotsubo cardiomyopathy associated with microscopic polyangiitis. A 70-year-old woman suddenly presented with ventricular dysfunction during the active phase of microscopic polyangiitis. The findings on echocardiograms and electrocardiograms were consistent with those of takotsubo cardiomyopathy. The ventricular dysfunction completely resolved after treatment with 40 mg/day of prednisolone and methylprednisolone pulse therapy. This unique type of cardiomyopathy can be a complication of microscopic polyangiitis.

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