Cerebral Atrophy and Convulsive Seizures after Recovery from Cerebral Edema and Coma in a Patient with Fulminant Hepatitis B

Suguru HONDA; Akira TANIGUCHI; Katsumasa MURAI; Shigeki KUZUHARA

doi:10.2169/internalmedicine.40.255

Suguru HONDA, Akira TANIGUCHI, Katsumasa MURAI, Shigeki KUZUHARA

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Keywords: fulminant hepatic failure, neurological complication, brain computed tomography, electroencephalography

JOURNAL FREE ACCESS

2001 Volume 40 Issue 3 Pages 255-258

DOI https://doi.org/10.2169/internalmedicine.40.255

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Abstract

We report a 48-year-old woman who developed convulsive seizures and cerebral atrophy after recovery from fulminant hepatitis B with coma and cerebral edema at the acute stage. Neurological disturbances and cerebral signs are rare sequelae of fulminant hepatic failure (FHF); only a few cases have reported in the literature. Cortical laminar necrosis secondary to cerebral edema or delayed neuronal death due to toxic substances may have caused delayed brain atrophy and epileptogenesis.
(Internal Medicine 40: 255-258, 2001)

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