Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Gastrointestinal Stromal Tumors of the Small Intestine That Expressed c-kit Protein
Natsuki HOSHINO, Tetsuya MURATA, Koji OKA, Keiki KAWAKAMI, Ken-ichiro HOSHINO, Shigeyuki SEKOGUCHI, Taka-aki SUGA, Akira NISHIMURA, Masami KATO, Masayuki HAMADA
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Keywords: small bowels, GISTs, CD117, CD 34, immunohistochemistry
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2000 Volume 39 Issue 11 Pages 914-919

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Abstract

We report two patients with gastrointestinal stromal tumors (GISTs) of the small intestine that expressed c-kit protein (CD117). One was a 68-year-old woman with epigastralgia and vomiting. A submucosal tumor of the upper jejunum was detected, and partial resection was carried out. The histology revealed a GIST negative for CD34 but positive for CD117. The other was a 42-year-old woman with progressive anemia, melena and lower abdominal pain. Intussusception was detected, and a partial resection was carried out. A submucosal tumor of the lower jejunum was noted. The histology revealed a GIST positive for both CD34 and CD117.
(Internal Medicine 39: 914-919, 2000)

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