A Family with Cases of Adult Onset Still's Disease and Psoriatic Arthritis
2000 Volume 39 Issue 1 Pages 77-79
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2000 Volume 39 Issue 1 Pages 77-79
Adult onset Still's disease is recognized as an adult variant of the systemic form of juvenile rheumatoid arthritis, whose disease-predisposition is still debated. On the other hand, the association between HLA subtypes and several groups of seronegative arthritis including psoriatic arthritis has been well documented. This report describes a family where adult onset Still's disease in a young man and psoriatic arthritis in his father were seen. Both patients were HLA-B39-positive, which was likely playing important pathogenic roles in the latter case. Clinical and immunological aspects of HLA-B39-related inflammatory diseases are also discussed.
(Internal Medicine 39: 77-79, 2000)
