Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Diabetic Ketoacidosis Associated with Guillain-Barré Syndrome with Autonomic Dysfunction
Setsuko FUJIWARAHiroyuki OSHIKAKenzo MOTOKIKenji KUBOYukiaki RYUJINMasahiro SHINOZAKITakuzo HANOIchiro NISHIO
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2000 Volume 39 Issue 6 Pages 495-498

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Abstract

A 37-year-old woman was admitted in a comatose state, after exhibiting fever and diarrhea. Diabetic ketoacidosis was diagnosed due to an increased blood glucose level (672 mg/dl), metabolic acidosis, and positive urinary ketone bodies. On the fifth hospital day, despite recovery from the critical state of ketoacidosis, the patient suffered from dysphagia, hypesthesia and motor weakness, followed by respiratory failure. Cerebrospinal fluid analysis was suggestive of Guillain-Barré syndrome (GBS). Autonomic dysfunction was manifested as tachycardia and mild hypertension in the acute stage. Marked orthostatic hypotension persisted long after paresis was improved, indicating an atypical clinical course of GBS.
(Internal Medicine 39: 495-498, 2000)

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© The Japanese Society of Internal Medicine
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