The Effect of Non-Activated Prothrombin Complex Concentrate (Proplex ® ST) on Intraperitoneal Hematoma in a Hemophilia A Patient with a Factor VIII Inhibitor

Hideo KAGAWA; Minori YASUZAWA; Yoshio OZAKI; Yoshihisa YAMAMOTO; Tatsuya KATSURADA; Shosaku NOMURA; Susumu OKUBO; Shirou FUKUHARA

doi:10.2169/internalmedicine.35.319

Hideo KAGAWA, Minori YASUZAWA, Yoshio OZAKI, Yoshihisa YAMAMOTO, Tatsuya KATSURADA, Shosaku NOMURA, Susumu OKUBO, Shirou FUKUHARA

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Keywords: bypass therapy, high-responder

JOURNAL FREE ACCESS

1996 Volume 35 Issue 4 Pages 319-322

DOI https://doi.org/10.2169/internalmedicine.35.319

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Abstract

A 28-year-old severe hemophiliac with a factor VIII inhibitor was admitted to our hospital with a massive and serious intraperitoneal hematoma. He was a high-responder patient showing maximal serum inhibitor levels as high as 255 Bethesda Units/ml (BU/ml). He was successfully treated with "bypass therapy" using a prothrombin complex concentrate (PCC).
(Internal Medicine 35: 319-322, 1996)

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