Superficial Esophageal Cancer in a Fanconi Anemia Patient That Was Treated Successfully by Endoscopic Submucosal Resection

Sachiyo Onishi; Masahiro Tajika; Tsutomu Tanaka; Makoto Ishihara; Yutaka Hirayama; Nobumasa Mizuno; Takamichi Kuwahara; Nozomi Okuno; Shinpei Matsumoto; Kazuhiro Toriyama; Yusuke Kurita; Masanori Obata; Yusuke Koide; Yasuhisa Hasegawa; Kazuo Hara; Yasumasa Niwa

doi:10.2169/internalmedicine.1434-18

CASE REPORTS

Superficial Esophageal Cancer in a Fanconi Anemia Patient That Was Treated Successfully by Endoscopic Submucosal Resection

Sachiyo Onishi, Masahiro Tajika, Tsutomu Tanaka, Makoto Ishihara, Yutaka Hirayama, Nobumasa Mizuno, Takamichi Kuwahara, Nozomi Okuno, Shinpei Matsumoto, Kazuhiro Toriyama, Yusuke Kurita, Masanori Obata, Yusuke Koide, Yasuhisa Hasegawa, Kazuo Hara, Yasumasa Niwa

Author information

Sachiyo Onishi
Department of Endoscopy, Aichi Cancer Center Hospital, Japan
Masahiro Tajika
Department of Endoscopy, Aichi Cancer Center Hospital, Japan
Tsutomu Tanaka
Department of Endoscopy, Aichi Cancer Center Hospital, Japan
Makoto Ishihara
Department of Endoscopy, Aichi Cancer Center Hospital, Japan
Yutaka Hirayama
Department of Endoscopy, Aichi Cancer Center Hospital, Japan
Nobumasa Mizuno
Department of Gastroenterology, Aichi Cancer Center Hospital, Japan
Takamichi Kuwahara
Department of Gastroenterology, Aichi Cancer Center Hospital, Japan
Nozomi Okuno
Department of Gastroenterology, Aichi Cancer Center Hospital, Japan
Shinpei Matsumoto
Department of Gastroenterology, Aichi Cancer Center Hospital, Japan
Kazuhiro Toriyama
Department of Endoscopy, Aichi Cancer Center Hospital, Japan
Yusuke Kurita
Department of Gastroenterology, Aichi Cancer Center Hospital, Japan
Masanori Obata
Department of Gastroenterology, Aichi Cancer Center Hospital, Japan
Yusuke Koide
Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Japan
Yasuhisa Hasegawa
Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Japan
Kazuo Hara
Department of Gastroenterology, Aichi Cancer Center Hospital, Japan
Yasumasa Niwa
Department of Endoscopy, Aichi Cancer Center Hospital, Japan

Keywords: Fanconi anemia, superficial esophageal cancer, endoscopic submucosal resection

JOURNAL OPEN ACCESS

2019 Volume 58 Issue 4 Pages 529-533

DOI https://doi.org/10.2169/internalmedicine.1434-18

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Details

Abstract

Fanconi anemia (FA) is a disorder of chromosomal fragility characterized by progression to aplastic anemia, myelodysplastic syndrome, and leukemia. FA patients are also predisposed to solid cancers. A case of FA in an adult patient who developed tongue and superficial esophageal cancers following hematopoietic stem cell transplantation is reported. This case was considered significant because it is the first reported case of superficial esophageal cancer in an FA patient that was treated successfully by endoscopic submucosal resection.

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