STEROIDAL SAPONINS GLYCOSIDES FROM FRUITS OF SOLANUM NODIFLORUM JACQ.

Document Type : Original Article

Authors

1 Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt.

2 Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt.

Abstract

From the methanolic extract of the fresh berries of Solanum nodiflorum Jacq. (Solanaceae), Four known steroidal saponins were reported and identified as: (20S)-3ß, 16 ß -dihydroxy preg-5-ene-22-carboxylic acid-(22,16)-lactone-3-8- chacotrioside (Dumoside 1) and 3 ß - dihydroxy pregn-5,16-dien-20-one 3-0- ß chacotrioside; (Aethienolone 4), 3-0-a-L- rhamnopyranosyl-(1→2)-a-L-rhamnopyranosyl-(1→4)- ß -D-glucopyranosyl (25R,26R)-spirost-5-ene-3ß, 17α, 26-triol 2 and ß -chacotriosyl-(22,26R)-furost-5-ene-3 ß,17α,22,26-tetraol-26-O- ß -D-glucopyranoside 3. Their structures were identified by extensive 1H-NMR, 13C-NMR and DEPT-13C-NMR data as well as comparison with reported spectroscopic data.