Condensation of 3a,b with some aromatic aldehydes afforded the Schiff bases (4a-f). Reaction of 3a,b with aromatic aldehydes and alkyl phosphites gave the corresponding amino phosphonates (5a-d). Heating 3a,b with 6a-f in POCl3 at 85 °C furnished the amino sulphonamides (7a- l). Acid hydrolysis of compounds 7a,b and 7k) furnished the amines (8a-c). Condensation of 3a, b with 9a,b afforded the cyclized product (10a,b). Reaction of 3a with halo esters afforded 12 and 13. Heating 3a,b with 14a-c afforded 15a-f. Hydrolysis of 15a,b afforded 16a,b. Fusion of 3a,b with 1,4-butane sultone gave sultams (18a,b). The antimicrobial activity o9f some products was tried
El-Barbary⃰, A. A., Sharaf, A. M., & E-Bader, B. (2016). Some Chemical Aspects of 1,2,4-triazine derivatives. Delta Journal of Science, 37(1), 73-85. doi: 10.21608/djs.2016.139921
MLA
A. A. El-Barbary⃰; A. M. Sharaf; Bader E-Bader. "Some Chemical Aspects of 1,2,4-triazine derivatives". Delta Journal of Science, 37, 1, 2016, 73-85. doi: 10.21608/djs.2016.139921
HARVARD
El-Barbary⃰, A. A., Sharaf, A. M., E-Bader, B. (2016). 'Some Chemical Aspects of 1,2,4-triazine derivatives', Delta Journal of Science, 37(1), pp. 73-85. doi: 10.21608/djs.2016.139921
VANCOUVER
El-Barbary⃰, A. A., Sharaf, A. M., E-Bader, B. Some Chemical Aspects of 1,2,4-triazine derivatives. Delta Journal of Science, 2016; 37(1): 73-85. doi: 10.21608/djs.2016.139921