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Terbium-Sensitized Fluorescence Method for the Determination of Pazufloxacin Mesilate and Its Application

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Abstract

A simple, rapid and highly sensitive fluorometric method for the determination of pazufloxacin mesilate (PZFX) is described. It is based on the formation of the complex [Tb(PZFX)2]3+, which shows the intensive characteristic bands of Tb3+. Optimum conditions for the determination were investigated. Under the optimum experimental condition, the fluorescence intensity responds linearly to the PZFX concentration in the range of 2.0 × 10−8–5.0 × 10−6 mol/l with a detection limit of 6.2 × 10−9 mol/l. The method has been successfully applied to the determination of PZFX in urine and serum samples.

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Authors and Affiliations

  1. Department of Chemistry, Beijing Normal University, Beijing, 100875, P. R. China

    Shilv Chen, Hongwu Ma, Huichun Zhao, Ruiqing Feng & Linpei Jin

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  1. Shilv Chen
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  2. Hongwu Ma
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  3. Huichun Zhao
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  4. Ruiqing Feng
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  5. Linpei Jin
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Correspondence to Huichun Zhao.

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Chen, S., Ma, H., Zhao, H. et al. Terbium-Sensitized Fluorescence Method for the Determination of Pazufloxacin Mesilate and Its Application. ANAL. SCI. 20, 1075–1078 (2004). https://doi.org/10.2116/analsci.20.1075

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  • DOI: https://doi.org/10.2116/analsci.20.1075

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