Hepatitis C asociada al abuso de sustancias: nunca tan cerca de un tratamiento sin Interferón

Roberto Muga, Paola Zuluaga, Arantza Sanvisens, Inmaculada Rivas, Daniel Fuster, Ferran Bolao, Jordi Tor, - Red de Trastornos Adictivos-RTA

Resumen


La infección por el virus de la hepatitis C (VHC) es un problema de Salud Pública de primera magnitud; cada año ocurren entre 3 y 4 millones de nuevas infecciones y de hecho, la hepatitis crónica C es una de las principales causas de enfermedad hepática en el mundo. Usar drogas por vía parenteral está en el origen de dos de cada tres nuevas infecciones por VHC en el mundo occidental.

El tratamiento de la hepatitis C va a cambiar en los próximos años. El cambio es debido a la aparición de los llamados Antivirales de Acción Directa (AAD), unos fármacos que actúan contra proteínas clave del ciclo vital del VHC y que serán más eficaces, mejor tolerados y se administrarán durante menos tiempo. En este sentido, la nueva guía de tratamiento de la OMS en 2014 ya incluye alguno de ellos en sus recomendaciones; los nuevos fármacos se utilizarán en combinación y probablemente se podrá prescindir del Interferón.

Con la aparición de más y mejores antivirales contra el VHC es probable que debamos revisar el modelo asistencial vigente y orientarlo hacia uno más ágil e integrador, que trate al mayor número posible de pacientes, incluyendo a aquellos con abuso de sustancias.


Palabras clave


Abuso de sustancias; hepatitis C; tratamiento; antivirales acción directa.

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Referencias


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DOI: https://doi.org/10.20882/adicciones.698

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