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Quality value transmitting of volatile components in personalized preparations:a case study of Menthae Haplocalycis HerbaChinese Full Text

LI Yi-ping;HONG Yan-long;SHEN Lan;FENG Yi;LIN Xiao;WANG You-jie;College of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine;Health Service Collaborative Innovation Center of Shanghai Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine;Engineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine, Ministry of Education,Shanghai University of Traditional Chinese Medicine;

Abstract: Considering the characteristic chromatograms and quality value transmitting of three volatile components, this study investigated the changes in volatile components of Menthae Haplocalycis Herba in each heating process of personalized preparations and identified the critical control points for the application of volatile components from traditional Chinese medicine in such preparations. The characteristic chromatograms of volatile components in Menthae Haplocalycis Herba were established by gas chromatography, followed by the quantitative determination of three volatile components menthone, menthol, and piperitone and the comparison of retention rates of volatile components during the crushing, extraction, concentration and drying of preparation products and their change rules in characteristic peaks. The results showed that the volatile components of Menthae Haplocalycis Herba were reduced in each process. The loss rate was low in the crushing process when the volatile component peaks were present, but high in the extraction and concentration processes, manifested as the absence of partial component peaks and the presence of new component peaks. The changes in volatile components of Chuanxiong Chatiao Granule in the drying process were compared with those in Chuanxiong Chatiao Pill, both of which were prepared from the raw Menthae Haplocalycis Herba powder, and the findings demonstrated that Chuanxiong Chatiao Pill was superior to Chuanxiong Chatiao Granule. This study confirmed that the retention rates of volatile components in Menthae Haplocalycis Herba were mostly affected by the extraction and concentration processes, and the packing of preparations helped to reduce the loss of volatile components in Menthae Haplocalycis Herba powder, which has provided reference for the application of Chinese medicinal materials containing volatile components in the personalized preparations.
  • DOI:

    10.19540/j.cnki.cjcmm.20210525.303

  • Series:

    (E) Medicine & Public Health

  • Subject:

    Traditional Chinese Medicinal Herbs

  • Classification Code:

    R283.6

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