The feelings of comfortableness and unpleasantness are the result of acts on the consciousness by information received through the five senses. There are indivisual differences in grasping feelings by subjective information. Therefore, it is important to use an index with objectivity. In this study, we examined the effect of two different sense stimulations on humans. We used an inipedance method which is a good index to know a person's emotion. The subjects were 8 adults. Sense of touch stimulation was given to the back with a massage machine. Classic music was used for the hearing stimulation. The measurement conditions were both at the same time and individually. The subjects reacted sensitively to the sense of touch stimulation. On the other band, the hearing stimulation reaction was dull. For the sense of touch stimulation, the subject's condition after stimulation in SIR did not return to the control condition before stimulation. We supposed that the sense of touch stimulation had some effect on humans. For two simultaneous stimulations, the reaction was different from that of the single stimulation. From these things, we clarified that various sense stimulations were affecting on humans. We can expect that application of sense stimulation gives an enhanced cure effect.