Gall bladder specimen following cholecystectomy: a resource

Authors

  • Bhanumati Giridharan Department of Surgery, ESIC Medical College and PGIMSR, Chennai, Tamil Nadu, India
  • P. Madhivadhanam Department of Surgery, ESIC Medical College and PGIMSR, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2349-2902.isj20170199

Keywords:

Cholecystectomy, Gall bladder disease, Histopathology

Abstract

Background: Gallbladder stones are very common and cholecystectomy is the most commonly performed surgery globally. Gallbladder stones have been reported to be the leading cause of cholecystectomies worldwide. Other mechanisms have also been known to constitute for cholecystectomy, but the evidence is still weak with the exact mechanism unknown. The present study thus aims to assess the importance of routine histopathology of the gall blabber following cholecystectomy.

Methods: The study is a retrospective one that employs the use of patient records to achieve the objective.

Results: The findings of the study depict a significant association between the findings of the histopathology, ultrasound and clinical features.

Conclusions: The researcher presents the relevance of histopathology with respect to ultrasound and clinical presentation of the patient, thereby stating the need for a routine gall bladder specimen following cholecystectomy.

Author Biography

Bhanumati Giridharan, Department of Surgery, ESIC Medical College and PGIMSR, Chennai, Tamil Nadu, India

PROFORMA

 

 

Name of the Candidate: Dr.Bhanumati Giridharan

Date of Birth & Age:     10-11-1966      48 years

 

Qualification

College & Univ.

Year

Registration No. of UG & PG with date

Name of the State Medical Council

MBBS

 

Indra Gandhi Medical college and hospital  Nagpur 

Nagpur university

1989

57750

29/3/1996

TheTamilnadu Medical Council,Chennai

MS (General Surgery)     

 

Indra Gandhi Medical college and hospital  Nagpur 

Nagpur university

1992

57750

29/3/1996

TheTamilnadu Medical Council,Chennai

 

Present Designation:      Associate Professor 

Department:general surgery

College:      ESIC  PGIMSR Medical College and Hospital                   

City:    K.K.Nagar Tamilnadu 

Nature of appointment: Contract

Position

Name of Institution

    From

    To

Total Experience in year

 

Resident,registrar

 

 

Post M.S Registrar

Indra Gandhi Medical College and Hospital Nagpur

Indra Gandhi Medical College and Hospital Nagpur 

Feb  1990

 

 

 

Nov 1992

 Nov 1992

 

 

 

March 1993

 

2yrs 9 months

 

 

 

3 months

 

 

Locum Lecture

 

 

 

Assistant Professor

Indra Gandhi Medical College and Hospital Nagpur

 

 

SRM Medical College and Hospital

Potheri

 

   4-3-93

 

 

 

 

    2-2-2005

 

30-6-93

 

 

 

 

1-3-2010

 

 3 months

 

 

 

5years 1 month

 

 

 

Associate Professor

 

 

 

Associate Professor

 

 

 

 

Associate Professor

SRM Medical College and Hospital

Potheri

 

Melmaruvatthur Adhi Parashakti

Medical college and research center

 

ESIC PGIMSR KK Nagar

 

   1-3-2010

 

 

  21-12-2011

 

 

 

 

  22-05-2015

 

31-5-2011

 

 

22-5- 2015

 

 

 

 

Till date

 

1 years 3 month

 

 

4 years 7 month

 

 

 

 

11 months

References

Underwood J. A recovery plan for histopathology. R Coll Path Bull. 2001;113:12-4.

Samad A. Gall bladder carcinoma in patients undergoing cholecystectomy for cholelithiasis. J Pak Med Assoc. 2005;55(11):497-9.

Tazuma S. Gallstone disease: epidemiology, pathogenesis, and classification of biliary stones (common bile duct and intrahepatic). Best Pract Res Clin Gastroenterol. 2006;20(6):1075-83.

Maki T. Pathogenesis of calcium bilirubinate gallstone: role of E. coli, beta-glucuronidase and coagulation by inorganic ions, polyelectrolytes and agitation. Ann Surg. 1966;164(1):90-100.

Singh V, Trikha B, Nain C, Singh K, Bose S. Epidemiology of gallstone disease in Chandigarh: a community-based study. J Gastroenterol Hepatol. 2001;16(5):560-3.

Sarin SK, Negi VS, Dewan R, Sasan S, Saraya A. High familial prevalence of gallstones in the first-degree relatives of gallstone patients. Hepatology. 1995;22(1):138-41.

Tandon RK, Saraya A, Paul S, Kapur BM. Dietary habits of gallstone patients in Northern India. J Clin Gastroenterol. 1996;22(1):23-7.

Sharma MP, Duphare HV, Nijhawan S, Dasarathy S. Gallstone disease in north India: clinical and ultrasound profile in a referral hospital. J Clin Gastroenterol. 1990;12(5):547-9.

Khuroo MS, Mahajan R, Zargar SA, Javid G, Munshi S. Prevalence of peptic ulcer in India: an endoscopic and epidemiological study in urban Kashmir. Gut. 1989;30(7):930-4.

Kapoor VK, Mcmichael AJ. Gallbladder cancer: an “Indian” disease. Natl Med J India. 2003;16(4):209-13.

Sheth S, Bedford A, Chopra S. Primary gallbladder cancer: recognition of risk factors and the role of prophylactic cholecystectomy. Am J Gastroenterol. 2000;95(6):1402-10.

Kapoor VK. Cholecystectomy in patients with asymptomatic gallstones to prevent gall bladder cancer- the case against. Indian J Gastroenterol. 2006;25(3):152-4.

Aydogdu I, Sari R, Ulu R, Sevinc A. The frequency of gallbladder stones in patients with pernicious anemia. J Surg Res. 2001;101(2):120-3.

Benvegnù L, Noventa F, Chemello L, Fattovich G, Alberti A. Prevalence and incidence of cholecystolithiasis in cirrhosis and relation to the etiology of liver disease. Digestion. 1997;58(3):293-8.

Fernandes NF, Schwesinger WH, Hilsenbeck SG, Gross GW, Bay MK, Sirinek KR. Laparoscopic cholecystectomy and cirrhosis: a case-control study of outcomes. Liver Transpl. 2000;6(3):340-4.

Grassi M, Allevato C, Mammucari S, Lazzari S, Nocchi S. The prevalence of gallstones in patients suffering from liver cirrhosis: a clinico-statistical study of 350 patients. Ital J Gastroenterol. 1992;24(6):342-6.

Iber FL, Caruso G, Polepalle C, Kuchipudi V, Chinoy M. Increasing prevalence of gallstones in male veterans with alcoholic cirrhosis. Am J Gastroenterol. 1990;85(12):1593-6.

Attili AF, Carulli N, Roda E, Barbara B, Capocaccia L, Menotti A. Epidemiology of gallstone disease in Italy: prevalence data of the multicenter Italian study on cholelithiasis. Am J Epidemiol. 1995;141(2):158-65.

Diehl AK. Epidemiology and natural history of gallstone disease. Gastroenterol Clin North Am. 1991;20(1):1-19.

Barbara L, Sama C, Labate AM, Taroni F, Rusticali AG, Festi D, et al. A population study on the prevalence of gallstone disease: the Sirmione study. Hepatology. 1987;7(5):913-7.

Jorgensen T. Prevalence of gallstones in a Danish population. Am J Epidemiol. 1987;126(5):912-21.

Kratzer WK, Chele V, Mason RA, Hill V, Hay B, Haug C, et al. Gallstone prevalence in Germany the ulm gallbladder stone study. Dig Dis Sci. 1998;43(6):1285-91.

Loria P, Dilengite MA, Bozzoli M, Carubbi F, Messora R, Sassatelli R, et al. Prevalence rates of gallstone disease in Italy - The Chianciano population study. Eur J Epidemiol. 1994;10(2):143-50.

Shaffer EA. Epidemiology and risk factors for gallstone disease: has the paradigm changed in the 21st century? Curr Gastroenterol Rep. 2005;7(2):132-40.

Channa N, Soomro A, Ghangro A. holecystectomy is becoming an increasingly common operation in Hyderabad and adjoining areas. Rawal Med J. 2007;32(2):128-30.

Murshid KR. Symptomatic gallstones: a disease of young Saudi women. Saudi J Gastroenterol. 1998;4(3):159-62.

Siddiqui FG, Memon AA, Abro AH, Sasoli NA, Ahmad L. Routine histopathology of gallbladder after elective cholecystectomy for gallstones: waste of resources or a justified act? BMC Surg. 2013;13(1):26.

Fletcher DR, Jones RM, Riordan B, Hardy KJ. Laparoscopic cholecystectomy for complicated gallstone disease. Surg Endosc. 1992;6(4):179-82.

Memon W, Khanzada T, Samad A, Kumar B. Histopathological spectrum of gall bladder specimens after cholecystectomy. Pakistan J Med Sci. 2011;27(3):533-6.

Weinstein D, Herbert M, Bendet N, Sandbank J, Halevy A. Incidental finding of gallbladder carcinoma. Isr Med Assoc J. 2002;4(5):334-46.

Johnson RC, Fligelstone LJ, Wheeler MH, Horgan K, Maughan TS. Laparoscopic cholecystectomy: incidental carcinoma of the gallbladder with abdominal wall and axillary node metastasis. HPB Surg. 1997;10(3):169-71.

Romano F, Franciosi C, Caprotti R, Fina S, Porta G, Visintini G, et al. Laparoscopic cholecystectomy and unsuspected gallbladder cancer. Eur J Surg Oncol. 2001;27(3):225-8.

Shih SP, Schulick RD, Cameron JL, Lillemoe KD, Pitt HA, Choti MA, et al. Gallbladder cancer: the role of laparoscopy and radical resection. Ann Surg. 2007;245(6):893-901.

Siddiqui F, Soraya N. An audit of cholecystectomy specimens. J Surg Pakistan. 2002;7:18-21.

Ayyaz M, Waris M, Fahim F. Presentation and etiological factors of cancer gall bladder in patients undergoing cholecystectomies at Mayo Hospital, Lahore. Ann King Edward Med Coll. 2001;7:138-140.

Nawaz T, Khan R, Malik A. Incidence of carcinoma gall bladder in cholelithiasis. Pakistan J Surg. 2000;16:33-6.

Ponce EC, Miquel JF, Muñoz N, Herrero R, Ferrecio C, Wistuba II, et al. Epidemiology and molecular pathology of gallbladder cancer. CA Cancer J Clin. 2001;51(6):349-64.

Behari A, Kapoor VK. Does gallbladder cancer divide India? Indian J Gastroenterol. 2010;29(1):3-7.

WHO. The Globocan Project. 2008 Available at http://globocan.iarc.fr/Default.aspx. Accessed on 12 July 2016.

Zoysa MIM, Silva SKLA, Illeperuma A. Is routine histological examination of gall bladder specimens justifiable? Ceylon Med J. 2010;55(1):13-6.

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Published

2017-01-25

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Original Research Articles