Can perioperative haemodynamics and opioid requirement in Abdominal Hysterectomy be influenced by a premedication drug?

Abstract

Background: Abdominal hysterectomy is a common surgery, usually done under Spinal anaesthesia. It would be greater if a premedication oral drug were available to reduce the perioperative use of opioids. The aim of the study was to find out whether gabapentin can reduce the perioperative dose of tramadol but without affecting perioperative haemodynamics.

Methods: This is a randomized double blinded controlled study. Patients undergoing Abdominal hysterectomy under Spinal anaesthesia were divided into two groups. One group was given gabapentin and another was given placebo as premedication drugs. Perioperative haemodynamics were monitored. Perioperative requirement of tramadol injection was estimated.

Results: No significant changes were noted in perioperative haemodynamics. Perioperative requirement of tramadol was reduced in gabapentin group.

Conclusions: Gabapentin does not affect perioperative haemodynamics. Gabapentin reduces perioperative requirement of tramadol.