A study of tubal ectopic pregnancy based on the histopathology of fallopian tubes in the age group of 20-35 years

  • Dr. Rudradev Meyur Associate Professor, Department of Gynaecology and Obstetrics, R G Kar Medical College, Kolkata, West Bengal, India
  • Dr. Anirban Sadhu Associate Professor, Department of Gynaecology and Obstetrics, R G Kar Medical College, 1, Khudiram Bose Sarani, Kolkata, West Bengal, India
  • Dr. Hironmoy Mondal Assistant Professor, Department of Anatomy, R G Kar Medical College, Kolkata, West Bengal, India
  • Dr. Rupkamal Das Professor, Department of Gynaecology and Obstetrics, R G Kar Medical College, Kolkata, West Bengal, India
Keywords: Ectopic pregnancy, Fallopian tube, Chorionic villi, Salpingitis, Trophoblasts

Abstract

Purpose: Ectopic pregnancy is a life-threatening condition for the mother. Disruptions of the fallopian tube are considered to be important in its pathogenesis. The present study was conducted to observe the histopathology of this dreaded disease which could lead to the development of suitable remedies.

Methods: Cases diagnosed with ectopic gestation in the fallopian tube who subsequently underwent salpingectomy were considered for the study. Histopathology of sections from the affected fallopian tubes was studied under the light microscope after staining with H and E.

Results: Most cases presented with amenorrhoea, whereas others had dysmenorrhoea, menorrhagia, and menometrorrhagia. Histopathologic findings included the presence of salpingitis (acute and chronic), calcification, sclerosed vessel and.

Conclusion: Past history of inflammatory diseases, especially PID plays an important role in the subsequent development of ectopic pregnancy. Its prevention and treatment can lead to a decrease in the incidence of ectopic pregnancy.

Downloads

Download data is not yet available.

References

Thonneau P, Hijazi Y, Goyaux N, Calvez T, Keita N. Ectopic pregnancy in Conakry, Guinea. Bull World Health Organ. 2002;80(5):365-370.

Howkins and Bourne Shaw's Text book of Gynecology, 12th Ed. Publishers B.I. Churchil Livingstone Pvt Ltd.

Odendaal HJ, Schaetzing AE, Kruger TK. Textbook of Clinical Gynecology. 2nd Ed. Juta Academic publisher. Cape Town, South Africa;2001.

Kamwendo F, Forslin L, Bodin L, Danielsson D. Epidemiology of ectopic pregnancy during a 28-year period and the role of pelvic inflammatory disease. Sex Transm Infect. 2000;76(1):28-32. doi: https://doi.org/10.1136/sti.76.1.28.

Mufti S, Rather S, Mufti S, Rangrez RA, Wasiqa, Khalida. Ectopic pregnancy: An analysis of 114 cases. JK Pract. 2012;17(4):20-23.

Yadav A, Prakash A, Sharma C, Pegu B, Saha MK. Trends of ectopic pregnancies in Andaman and Nicobar Islands. Int J Reprod Contracept Obstet Gynecol. 2017;6(1):15-19. doi: http://dx.doi.org/10.18203/2320-1770.ijrcog20164499.

Carleton HM, Drury RAB, Wallington EA. Carleton’s Histological Technique. 4th ed. London: Oxford University Press; 1967. Chapter 3, Fixation;40-1.

Carleton HM, Drury RAB, Wallington EA. Carleton’s Histological Technique. 4th ed. London: Oxford University Press; 1967. Chapter 4, Preparation of Tissues for Microtomy;57.

Carleton HM, Drury RAB, Wallington EA. Carleton’s Histological Technique. 4th ed. London: Oxford University Press; 1967. Chapter 5, Microtomy;78-85.

Carleton HM, Drury RAB, Wallington EA. Carleton’s Histological Technique. 4th ed. London: Oxford University Press; 1967. Chapter 7, General Staining Procedures;129.

Soren M, Patnaik R, Sarangi BK. A clinical study on ectopic pregnancy. Int J Res Med Sci. 2017;5(11):4776-4782. doi: http://dx.doi.org/10.18203/2320-6012.ijrms20174671.

Rose Jophy R, Thomas A, Mhaskar A. Ectopic pregnancy 5 years’ experience. J Obstet Gynecol India. 2002;52(4):55-58.

Pendse V. Ectopic pregnancy: a review of 110 cases. J Obstet Gynecol Ind. 1981;31:100-105.

Arora R, Rathore AM, Habeebullah S, Oumachigui A. Ectopic pregnancy--changing trends. J Indian Med Assoc. 1998;96(2):53-54.

Kharat D, Giri PG, Fonseca M. A study of epidemiology of ectopic pregnancies in a tertiary care hospital of

Mumbai, India. Int J Reprod Contracept Obstet Gynecol. 2017;6(9):3942-3946. doi: http://dx.doi.org/10.18203/2320-1770.ijrcog20174040.

Dahiya N, Singh S, Kalra R, Sen R, Kumar S. Histopathological changes associated with ectopic tubal pregnancy. IJPSR. 2011;2(4):929-933.

Kutluay L, Vicdan K, Turan C, Batioglu S, Oguz S, Gokmen O. Tubal histopathology in ectopic pregnancies. Euro J Obstet Gyncecol. 1994;57(2):91-94. doi: https://doi.org/10.1016/0028-2243(94)90049-3.

Pranshu S, Bishnoi R. Histopathological changes in ectopic tubal pregnancy. IJSR. 2018;7(2):29-30.

Dubuisson JB, Aubriot FX, Cardone V, Vacher-Lavenu MC. Tubal causes of ectopic pregnancy. Fertil Steril. 1986;46(5):970-972. doi: https://doi.org/10.1016/S0015-0282(16)49846-8.

Green LK, Kott ML. Histopathologic findings in ectopic tubal pregnancy. Int J Obstet Gynaecol Pathol. 1989;8(3):255-256. doi: https://doi.org/10.1097/00004347-198909000-00009.

Persaud V. Etiology of tubal ectopic pregnancy: radiologic and pathologic studies. Obstet Gynecol. 1970;36(2):257-263.

CITATION
DOI: 10.17511/ijmrr.2020.i01.14
Published: 2020-02-26
How to Cite
1.
Meyur R, Sadhu DA, Mondal H, Das R. A study of tubal ectopic pregnancy based on the histopathology of fallopian tubes in the age group of 20-35 years. Int J Med Res Rev [Internet]. 2020Feb.26 [cited 2024Mar.29];8(1):92-6. Available from: https://ijmrr.medresearch.in/index.php/ijmrr/article/view/1148
Section
Original Article