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lncRNA NEAT1 regulates fibrosis and inflammatory response induced by nonalcoholic fatty liver by regulating miR-506/GLI3 Volume 30, numéro 3, September 2019

Illustrations


  • Figure 1

  • Figure 2

  • Figure 3

  • Figure 4

  • Figure 5
Auteurs
1 Department of Gastroenterology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, P.R China
2 Department of Pharmacy, Wenzhou People's Hospital, Wenzhou 325000, Zhejiang Province, P.R China
* Corresponding author: Dr. Hua-Qin Guan, Department of Gastroenterology, The First Affiliated Hospital of Wenzhou Medical University, New Campus of Nanbaixiang Wenyi First Hospital, Ouhai District, Wenzhou 325000, Zhejiang Province, P.R China

Background

As one of the most common liver disorders worldwide, nonalcoholic fatty liver disease (NAFLD) begins with the abnormal accumulation of triglyceride (TG) in the liver and can lead to inflammation and fibrosis. Long noncoding RNA (lncRNA) NEAT1 was reported to promote NAFLD progress. However, its molecular mechanism in NAFLD was not fully clear.