The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Inhibitory Effect of Liposome-Encapsulated Penicillin G on Growth of Listeria monocytogenes in Mouse Macrophages
MASAHIKO ITO, EIKO ISHIDA, FUMINORI TANABE, NORIO MORI, SHIRO SHIGETA
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Keywords: Listeria monocytogenes, liposome-penicillin G, macrophages
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1986 Volume 150 Issue 3 Pages 281-286

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Abstract

ITO, M., ISHIDA, E., TANABE, F., MORI, N. and SHIGETA, S. Inhibitory Effect of Liposome-Encapsulated Penicillin G on Growth of Listeria monocytogenes in Mouse Macrophages. Tohoku J. exp. Med., 1986, 150 (3), 281-286-Administration of penicillin G encapsulated in liposomes inhibited the proliferation of Listeria which infected mouse intraperitoneal resident macrophages whereas free penicillin G and/or liposomes did not. This result suggests that administration of antibiotics encapsulated in liposomes is an effective treatment for the intracellular infection.

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