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Dyshormia in focal epilepsy

Disormia em Epilepsia Focal

A 37-year-old man was evaluated for recurrent episodes of impaired awareness since childhood. EEG showed right temporal focal dyshormia (Figure 1). MRI revealed a right temporal mass (Figure 2).

Figure 1
Electroencephalographic abnormalities in focal dyshormia. A) and B) Right temporal epileptiform K-complexes during N2 sleep (arrows).

Figure 2
Neuroimaging showing a right temporal mass. A) coronal and B) axial non-contrast T2-FLAIR-weighted brain MRI shows a hyperintense right posterior temporal lobe lesion with heterogeneous internal signal (arrows). Pathology revealed a dysembryoplastic neuroepithelial tumor, WHO grade I.

Niedermeyer coined the term “dyshormia” to define epileptiform discharges that occur in conjunction with K-complexes on arousal from sleep11. Niedermeyer E. Epileptiform K complexes. Am J Electroneurodiagnostic Technol. 2008 Mar;48(1):48-51.. Although dyshormia was originally described in generalized epilepsies11. Niedermeyer E. Epileptiform K complexes. Am J Electroneurodiagnostic Technol. 2008 Mar;48(1):48-51., unilateral, focal dyshormia is occasionally seen in focal epilepsies22. Geyer JD, Carney PR, Gilliam F. Focal epileptiform spikes in conjuction with K-complexes. J Clin Neurophysiol. 2006 Oct;23(5):436-9. https://doi.org/10.1097/01.wnp.0000228499.92313.d6
https://doi.org/10.1097/01.wnp.000022849...
.

In focal epilepsies, epileptiform discharges associated with K-complexes are typically ipsilateral to the epileptogenic zone, and are more common in frontal than in temporal lobe epilepsies22. Geyer JD, Carney PR, Gilliam F. Focal epileptiform spikes in conjuction with K-complexes. J Clin Neurophysiol. 2006 Oct;23(5):436-9. https://doi.org/10.1097/01.wnp.0000228499.92313.d6
https://doi.org/10.1097/01.wnp.000022849...
. Their presence can assist in localization of epileptogenic regions.

References

  • 1
    Niedermeyer E. Epileptiform K complexes. Am J Electroneurodiagnostic Technol. 2008 Mar;48(1):48-51.
  • 2
    Geyer JD, Carney PR, Gilliam F. Focal epileptiform spikes in conjuction with K-complexes. J Clin Neurophysiol. 2006 Oct;23(5):436-9. https://doi.org/10.1097/01.wnp.0000228499.92313.d6
    » https://doi.org/10.1097/01.wnp.0000228499.92313.d6

Publication Dates

  • Publication in this collection
    July 2018

History

  • Received
    22 Feb 2018
  • Accepted
    25 Mar 2018
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