Journal of Korean Society of Occupational and Environmental Hygiene (한국산업보건학회지)

Korean Industrial Hygiene Association (한국산업보건학회)
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Effect of Non-thermal Dielectric Barrier Discharge Plasma by Air Volume against Mycobacterium Tuberculosis

비열 유전체장벽방전 플라즈마 발생기의 풍량에 따른 결핵균 성장억제 효능

  • 손은순 ((재)국제결핵연구소) ;
  • 김용희 ((주)신영에어텍 공기과학연구소) ;
  • 백남원 ((주)신영에어텍 공기과학연구소) ;
  • 이일영 ((주)신영에어텍 공기과학연구소) ;
  • 김은화 ((주)신영에어텍 공기과학연구소) ;
  • 박해룡 (경남대학교 바이오융합학부) ;
  • 이종석 ((재)국제결핵연구소)
  • Received : 2019.06.19
  • Accepted : 2019.08.25
  • Published : 2019.09.30
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Abstract

Objectives: The objective of this study was to evaluate the inhibitory effect of non-thermal dielectric barrier discharge (DBD) plasma by air volume against Mycobacterium tuberculosis (MTB). Methods: Plasma generators (TB-300, Shinyoung Airtec, Seongnam-si, Korea) were operated in a 2A type biosafety cabinet. The plasma generator was set to a wind flow rate of 14 ($80m^3/h$), 18 ($110m^3/h$), and 22 ($150m^3/h$), and exposure times were set to 0 hours, 3 hours, 6 hours, 9 hours, and 24 hours. Results: The inhibitory effects of plasma at air volume 14 with prolonged exposure time of three hours was 20%, 64% at six hours, 82.3% at nine hours, and 100% after 24 hours exposure. With air volume of 18, the inhibitory effects upon plasma exposure were 36% for three hours, and 100% from 24 hours. Greater air volume resulted in greater inhibition of tuberculosis bacterial growth. In particular, the maximum inhibitory effect (100%) was shown in air volume of 22 ($150m^3/h$) after three hours of plasma exposure. Conclusions: The results showed the correlating inhibitory effects of plasma on the growth of MTB in combination with increasing plasma exposure time and air volume.

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References

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