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Needle-based Delivery Devices in Dentistry

DISCOVERIES (ISSN 2359-7232), 2020, July-September issue

CITATION: 

Batra P, Dawar A, Miglani SMicroneedles and Nanopatches-Based Delivery Devices in Dentistry. Discoveries 2020, 8(3): e116. DOI: 10.15190/d.2020.13


Submitted: August 18, 2020; Revision: September 19, 2020; Accepted: September 19, 2020; Published: September 30, 2020; 

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Microneedles and Nanopatches-Based Delivery Devices in Dentistry

Panchali Batra (1), Anika Dawar (2,*), Sanjay Miglani (3)

(1) Department of Orthodontics, Faculty of Dentistry, Jamia Millia Islamia, (Central University), New Delhi, India

(2) Division of Periodontics, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India

(3) Department of Conservative Dentistry and Endodontics, Faculty of Dentistry, Jamia Millia Islamia (Central University), New Delhi, India


*Corresponding author: Dr. Anika Dawar, Division of Periodontics, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India; Phone: +91-9953270897; Email: anika_doc@aiims.edu

Abstract

Needle-based devices are evolving as a promising diagnostic and therapeutic tool in the field of medicine. They can be used for drug delivery, as well as extraction of fluids, for systemic and local effects. The conventional methods of drug delivery require repeated dosing in the oral cavity due to the presence of saliva. Hence delivery systems, such as needle-based devices that could provide sustained release of the drug in the oral cavity, are required. These devices could also be a useful adjunct in diagnosis and therapy of oral cancers, delivering anti-cariogenic and antiplaque agents, for remote monitoring of oral health, and for administering painless and fearless local anesthesia. Since they offer many advantages, such as increased compliance, absence of needle phobia, they are painless, safe, self-applicable and are minimally invasive, they will have a major impact in the field of dentistry. This paper summarizes the various types of needle-based devices and their manufacturing technologies. The manuscript aims to serve as a foundational review that highlights and proposes several current and prospective impactful applications of these devices in various fields of dentistry.


Access full text of the manuscript here: 

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