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BY-NC-ND 3.0 license Open Access Published by De Gruyter June 2, 2014

New Semisynthetic Antimicrobial Labdane-Type Diterpenoids Derived from the Resin “Ladano” of Cistus creticus

  • Eleftherios Kalpoutzaki , Nektarios Aligiannis , Sofia Mitaku , Catherine Harvala and Alexios-Leandros Skaltsounis EMAIL logo

Abstract

The antimicrobial activity of fifteen semisynthetic labdane-type diterpenes derived from the two major natural compounds 3 and 4 of the resin "ladano" of Cistus creticus is reported. The chloroethyl carbamidic esters 15 and 20 showed the strongest antimicrobial activity against Gram (+), Gram (-) bacteria and pathogenic fungi.

Received: 2000-9-20
Revised: 2000-11-10
Published Online: 2014-6-2
Published in Print: 2001-2-1

© 1946 – 2014: Verlag der Zeitschrift für Naturforschung

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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