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BY-NC-ND 3.0 license Open Access Published by De Gruyter June 2, 2014

Potent Free Radical Scavenging Activity of Propol Isolated from Brazilian Propolis

  • Purusotam Basnet , Tetsuya Matsuno and Richard Neidlein

Abstract

We evaluated free radical scavenging activity of the water, methanol and chloroform ex­tracts of propolis in 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical and xanthine-xanthine oxidase (XOD) generated superoxide anion assay systems. The free radical scavenging activity guided fractionation and chemical analysis led to the isolation of a new compound, propol {3-[4-hydroxy-3-(3-oxo-but-1-enyl)-phenyl]-acrylic acid) from the water extract, which was more potent than most common antioxidants such as vitamin C and vitamin E (α-tocopherol) in these assay systems.

Received: 1997-8-7
Revised: 1997-9-19
Published Online: 2014-6-2
Published in Print: 1997-12-1

© 1946 – 2014: Verlag der Zeitschrift für Naturforschung

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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