The aminomethyl-group of porphobilinogen reacted as an alkylating agent in alkaline solution with primary and secondary amines, amino alcohols, certain amino acids, and C-H acidic compounds. The uroporphyrinogen formation competed with these reactions. An elimination-addition mechanism is discussed. The possibility of this reaction acting a part in the biosynthesis of corrin ring formation is indicated.
Received: 1970-11-3
Published Online: 2014-6-2
Published in Print: 1971-2-1
© 1946 – 2014: Verlag der Zeitschrift für Naturforschung
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