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Licensed Unlicensed Requires Authentication Published by De Gruyter May 10, 2012

Non-invasive measurement of adrenal response after standardized exercise tests in prepubertal children

  • Sigrid M. Heijsman , Nicoline F. Koers , Gianni Bocca , Betty S. van der Veen , Maaike Appelhof and Arvid W.A. Kamps EMAIL logo

Abstract

Objective: To determine the feasibility of non-invasive evaluation of adrenal response in healthy prepubertal children by standardized exercise tests.

Methods: On separate occasions, healthy prepubertal children performed a submaximal cycling test, a maximal cycling test, and a 20-m shuttle-run test. Salivary cortisol levels were determined before exercise, and 1 and 15 min after exercise.

Results: Immediately after cessation of the cycling and shuttle-run tests, salivary cortisol levels remained unchanged or decreased. Fifteen minutes after the shuttle-run test, salivary cortisol levels increased significantly. This increase in salivary cortisol levels was not observed 15 min after the cessation of the cycling tests.

Conclusion: The results of this study demonstrate a different response in salivary cortisol levels after standardized cycling and running tests in prepubertal children. The increase in salivary cortisol levels found after a short standardized running test suggests that this may be a practical non-invasive method for evaluating adrenal response in healthy prepubertal children.


Corresponding author: Arvid W.A. Kamps, MD, PhD, Department of Paediatrics, Medical Centre Leeuwarden, P.O. Box 888, 8901 BR Leeuwarden, The Netherlands Phone: +31 58 2863389, Fax: +31 58 2863390

Received: 2012-2-22
Accepted: 2012-3-21
Published Online: 2012-05-10
Published in Print: 2012-06-01

©2012 by Walter de Gruyter Berlin Boston

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