Funding source: Pusan National University Hospital
Research funding: This work was supported by clinical research grant of Pusan National University Hospital in 2020.
Author contributions: This study was designed and organized by SY Moon and KR Jun. D-W Yoo wrote the first draft and performed statistical analysis. JH Lee and WJ Hwang collected the remnant samples, analyzed the original and mixed samples. KR Jun helped additional tests with Sekisui reagents and gave an idea to initiate this study. HH Kim and SM Lee are advised to the research protocol and responsible for the laboratory tests. All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
Competing interests: All authors state no conflict of interest in this research.
Informed consent: Informed consent was obtained from all individuals included in this study.
Ethical approval: This study was approved by the Institutional Review Board in our hospital (H-2007-009-093).
References
1. Martinello, F, da Silva, EL. Mechanism of ascorbate interference in biochemical tests that use peroxide and peroxidase to generate chromophore. Clin Chim Acta 2006; 373: 108–16. https://doi.org/10.1016/j.cca.2006.05.012.Search in Google Scholar
2. Inamdar, KV, Raghavan, KG, Pradhan, DS. Five treatment procedures evaluated for the elimination of ascorbate interference in the enzymatic determination of urinary oxalate. Clin Chem 1991; 37: 864–8. https://doi.org/10.1093/clinchem/37.6.864.Search in Google Scholar
3. Nah, H, Yim, J, Lee, SG, Lim, JB, Kim, JH. Ascorbate oxidase minimizes interference by high-concentration ascorbate in total cholesterol assays. Ann Lab Med 2016; 36: 188–90. https://doi.org/10.3343/alm.2016.36.2.188.Search in Google Scholar
4. Lee, YW. Annual report on the external quality assessment scheme for general chemistry in Korea (2017). J Lab Med Qual Assur 2018; 40: 113–27. https://doi.org/10.15263/jlmqa.2015.37.3.115.Search in Google Scholar
5. Medical Statistic Information. Services (tests, procedures) statistics [Online]; 2020. Available from: http://opendata.hira.or.kr/op/opc/olapDiagBhvInfo.do.Search in Google Scholar
6. Kuchmak, M, Taylor, L, Olansky, A. Suitability of frozen and lyophilized reference sera for cholesterol and triglyceride determinations. Clin Chim Acta 1982; 120: 261–71. https://doi.org/10.1016/0009-8981(82)90163-2.Search in Google Scholar
7. Comstock, GW, Norkus, EP, Hoffman, SC, Xu, M-W, Helzlsouer, KJ. Stability of ascorbic acid, carotenoids, retinol, and tocopherols in plasma stored at-70 degrees C for 4 years. Cancer Epidemiol Biomark Prev 1995; 4: 505–7. https://cebp.aacrjournals.org/content/4/5/505.Search in Google Scholar
8. Bobrowicz, E, Naskalski, JW, Siedlecki, A. Preanalytical factors in human plasma ascorbate assay. Clin Chim Acta 2001; 314: 237–9. https://doi.org/10.1016/s0009-8981(01)00577-0.Search in Google Scholar
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