Author contributions: The author has accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: None declared.
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
References
1. Diamandis EP, Li M. The side effects of translational omics: overtesting, overdiagnosis, overtreatment. Clin Chem Lab Med 2016;54:389–96.10.1515/cclm-2015-0762Search in Google Scholar PubMed
2. Wan JC, Massie C, Garcia-Corbacho J, Mouliere F, Benton JD, Caldas C, et al. Liquid biopsies come of age: towards implementation of circulating tumour DNA. Nat Rev Cancer 2017;17:223–38.10.1038/nrc.2017.7Search in Google Scholar PubMed
3. Diamandis EP, Fiala C. Can circulating tumor DNA be used for direct and early stage cancer detection? F1000Res 2017;6:2129.10.12688/f1000research.13440.1Search in Google Scholar PubMed PubMed Central
4. Aravanis AM, Lee M, Klausner RD. Next-generation sequencing of circulating tumor DNA for early cancer detection. Cell 2017;168:571–4.10.1016/j.cell.2017.01.030Search in Google Scholar PubMed
5. Cohen JD, Li L, Wang Y, Thoburn C, Afsari B, Danilova L, et al. Detection and localization of surgically resectable cancers with a multi-analyte blood test. Science 2018;359:926–30.10.1126/science.aar3247Search in Google Scholar PubMed PubMed Central
6. Liu MC, Maddala T, Aravanis A, Hubbel E, Beusang JF, Filippova D, et al. Breast cancer cell-free DNA (cfDNA) profiles reflect underlying tumor biology: The Circulating Cell-Free Genome Atlas (CCGA) study. J Clin Oncol 2018;36(suppl: abstr536):12021.10.1200/JCO.2018.36.15_suppl.536Search in Google Scholar
7. Klein EA, Hubbel E, Maddala T, Aravanis A, Beusang JF, Filippova D, et al. Development of a comprehensive cell-free DNA (cfDNA) assay for early detection of multiple tumor types: The Circulating Cell Free Genome Atlas (CCGA) study. J Clin Oncol 2018;36(suppl: abstr12021):536.10.1200/JCO.2018.36.15_suppl.12021Search in Google Scholar
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