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Licensed Unlicensed Requires Authentication Published by De Gruyter September 11, 2018

Impact of continuous renal replacement therapy (CRRT) and other extracorporeal support techniques on procalcitonin guided antibiotic therapy in critically ill patients with septic shock

  • Giancarlo Ceccarelli ORCID logo EMAIL logo , Francesco Alessandri , Valeria Sargentini , Maria Domenica D’Alessandro , Martina Spaziante , Alessandra Bachetoni , Santo Morabito and Mario Venditti

Corresponding author: Giancarlo Ceccarelli, MD, PhD, MSc, Department of Public Health and Infectious Diseases, Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy, Phone: 0039-06-49970905

  1. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Employment or leadership: None declared.

  4. Honorarium: None declared.

  5. Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.

References

1. Bartoletti M, Antonelli M, Bruno Blasi FA, Casagranda I, Chieregato A, Fumagalli R, et al. Procalcitonin-guided antibiotic therapy: an expert consensus. Clin Chem Lab Med 2018; 56:1223–9.10.1515/cclm-2018-0259Search in Google Scholar PubMed

2. Level C, Chauveau P, Guisset O, Cazin MC, Lasseur C, Gabinsky C, et al. Mass transfer, clearance and plasma concentration of procalcitonin during continuous venovenous hemofiltration in patients with septic shock and acute oliguric renal failure. Crit Care 2003;7:R160–6.10.1186/cc2372Search in Google Scholar PubMed PubMed Central

3. Kim DW, Cho HJ, Kim GS, Song SY, Na KJ, Oh SG, et al. Predictive value of procalcitonin for infection and survival in adult cardiogenic shock patients treated with extracorporeal membrane oxygenation. Chonnam Med J 2018;54:48–54.10.4068/cmj.2018.54.1.48Search in Google Scholar PubMed PubMed Central

4. Rungatscher A, Merlini A, De Rita F, Lucchese G, Barozzi L, Faggian G, et al. Diagnosis of infection in paediatric veno-arterial cardiac extracorporeal membrane oxygenation: role of procalcitonin and C-reactive protein. Eur J Cardiothorac Surg 2013;43:1043–9.10.1093/ejcts/ezs524Search in Google Scholar PubMed

5. Tan VE, Moore WS, Chopra A, Cies JJ. Association of procalcitonin values and bacterial infections in pediatric patients receiving extracorporeal membrane oxygenation. Perfusion 2018;33: 278–82.10.1177/0267659117743806Search in Google Scholar PubMed

Received: 2018-06-29
Accepted: 2018-08-13
Published Online: 2018-09-11
Published in Print: 2019-04-24

©2019 Walter de Gruyter GmbH, Berlin/Boston

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