Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: None declared.
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
References
1. Kricka LJ. Human anti-animal antibody interferences in immunological assays. Clin Chem 1999;45:942–56.10.1093/clinchem/45.7.942Search in Google Scholar
2. Bolstad N, Warren DJ, Nustad K. Heterophilic antibody interference in immunometric assays. Best Pract Res Clin Endocrinol Metab. 2013;27:647–61.10.1016/j.beem.2013.05.011Search in Google Scholar PubMed
3. Preissner CM, Dodge LA, O’Kane DJ, Singh RJ, Grebe SKG. Prevalence of heterophilic antibody interference in eight automated tumor marker immunoassays. Clin Chem 2005;51:208–10.10.1373/clinchem.2004.040501Search in Google Scholar PubMed
4. Bolstad N, Warren DJ, Bjerner J, Kravdal G, Schwettmann L, Olsen KH, et al. Heterophilic antibody interference in commercial immunoassays; a screening study using paired native and pre-blocked sera. Clin Chem Lab Med 2011;49:2001–6.10.1515/CCLM.2011.702Search in Google Scholar PubMed
5. Gulbahar O, Degertekin CK, Akturk M, Yalcin MM, Kalan I, Atikeler GF, et al. A case with immunoassay interferences in the measurement of multiple hormones. J Clin Endocrinol Metab 2015;100:2147–53.10.1210/jc.2014-4023Search in Google Scholar PubMed
6. Saleem M, Lewis JG, Florkowski CM, Kulligan GP, George PM, Hale P. A patient with pseudo-Addison’s disease and falsely elevated thyroxine due to interference in serum cortisol and free thyroxine immunoassays by two different mechanisms. Ann Clin Biochem 2009;46:172–5.10.1258/acb.2008.008224Search in Google Scholar PubMed
7. Fiad TM, Duffy J, McKenna TJ. Multiple spuriously abnormal thyroid function indices due to heterophilic antibodies. Clin Endocrinol (Oxf) 1994;41:391–5.10.1111/j.1365-2265.1994.tb02563.xSearch in Google Scholar PubMed
8. Brugts MP, Luermans JG, Lentjes EG, van Trooyen-van Vrouwerff NJ, van der Horst FA, Slee PH, et al. Heterophilic antibodies may be a cause of falsely low total IGF1 levels. Eur J Endocrinol 2009;161:561–5.10.1530/EJE-09-0316Search in Google Scholar PubMed
9. Bjerner J, Bolstad N, Piehler A. Belief is only half the truth–or why screening for heterophilic antibody interference in certain assays makes double sense. Ann Clin Biochem 2012;49:381–6.10.1258/acb.2012.011228Search in Google Scholar PubMed
©2016 by De Gruyter
