Spontaneous Recovery from Hypopituitarism in a Man with Lymphocytic Hypophysitis A Case Report

HIROSHI NOTO; KAZUHISA TSUKAMOTO; SHUHEI HAYASHI; KOJI TAKANO; TOSHIRO FUJITA; SATOSHI KIMURA

doi:10.1507/endocrj.48.483

Spontaneous Recovery from Hypopituitarism in a Man with Lymphocytic Hypophysitis

A Case Report

HIROSHI NOTO, KAZUHISA TSUKAMOTO, SHUHEI HAYASHI, KOJI TAKANO, TOSHIRO FUJITA, SATOSHI KIMURA

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Keywords: Lymphocytic hypophysitis, Hypopituitarism

JOURNAL FREE ACCESS

2001 Volume 48 Issue 4 Pages 483-486

DOI https://doi.org/10.1507/endocrj.48.483

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Abstract

A 50-year-old man presented with hypopituitarism and a pituitary lesion on magnetic resonance imaging scan. He was diagnosed as having lymphocytic hypophysitis, and replacement therapy with hydrocortisone and thyroxine was started. He regained normal pituitary function after 10 months. Reports of spontaneous recovery from Lymphocytic hypophysitis in men are rare. While the natural history of lymphocytic hypophysitis remains elusive and its management is not well established, our report shows that spontaneous resolution may occur with steroid supplementation even in men.

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