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No-Reference image quality metrics for structural MRI

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Abstract

Neuroimagery must be visually checked for unacceptable levels of distortion prior to processing. However, inspection is time-consuming, unreliable for detecting subtle distortions and often subjective. With the increasing volume of neuroimagery, objective measures of quality are needed in order to automate screening. To address this need, we have assessed the effectiveness of no-reference image quality measures, which quantify quality inherent to a single image. A data set of 1001 magnetic resonance images (MRIs) recorded from 143 subjects was used for this evaluation. The MRI images were artificially distorted with two levels of either additive Gaussian noise or intensity nouniformity created from a linear model. A total of 239 different quality measures were defined from seven overall families and used to discriminate images for the type and level of distortion. Analysis of Variance identified two families of quality measure that were most effective: one based on Natural Scene Statistics and one originally developed to measure distortion caused by image compression. Measures from both families reliably discriminated among undistorted images, noisy images, and images distorted by intensity nonuniformity. The best quality measures were sensitive only to the distortion category and were not significantly affected by other factors. The results are encouraging enough that several quality measures are being incorporated in a real world MRI test bed.

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References

  • Avcibas, A., Sankur, B., and Seafood, K. (2002). Statistical evaluation of image quality measures. J. Electron. Imag. 11(2), 206–223.

    Article  Google Scholar 

  • Carley-Spencer, M., Woodard, J., Dixon, J., and Cornett, T. (2005) Content-based image retrieval and image quality of structural MRI. Neuroimage Abs (26). 11th Annual Meeting of the Organization for Human Brain Mapping. Toronto.

  • Cohen, L. (1989) Time-frequency distributions—A Review, Proc. IEEE 77, 941–981.

    Article  Google Scholar 

  • Collins, D., Neelin, P., Peters, T., and Evans, A. (1994) Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space. J. Comput. Assist. Tomogr. 18(2), 192–205.

    Article  CAS  Google Scholar 

  • Collins, D., Zijdenbos, A., Kollokian, V., et al. (1998). Design and construction of a realistic digital brain phantom. IEEE Trans. Med. Imag. 17(3), 463–468.

    Article  CAS  Google Scholar 

  • Debrunner, V., Ozaydm, M., and Prezebinda, T. (1999) Resolution in time-frequency, IEEE Trans. Signal Process. 47(3), 783–788.

    Article  Google Scholar 

  • Eskicioglu, A., Fisher, P., and Chen, S. (1995) Image quality measures and their performance. IEEE Trans. Commun. 43(12), 2959–2965.

    Article  Google Scholar 

  • Hadjidemetriou, E., Grossberg, M., and Nayar S. (2004) Multiresolution histograms and theiruse for recognition. IEEE Trans. PAMI 2(7), 831–847.

    Google Scholar 

  • Hoyt, J., Smith, K., Hamilton, G., Cornett, T., and Carley-Spencer, M. (2005) NeuroServ: An Information System for Storage, Retrieval, Sharing, and Discovery of Human Brain Imaging Data-With Application to DTI. Neuroimage Abs (26) (2005). 11th Annual Meeting of the Organization for Human Brain Mapping. Toronto.

  • Jayant, N. and Noll, P. (1984) Digital Coding of Waveforms, Englewood Cliffs, Prentice Hall.

    Google Scholar 

  • Kwan, R., Evans, A., and Pike, G. (1999) MRI simulation-based evaluation of image-processing and classification methods. IEEE Trans. Med. Imag. 18(11), 1085–1097.

    Article  CAS  Google Scholar 

  • Martin, G., Morison, W., and Durrani, T. (2004) Fast and accurate image registration using Tsallis entropy and simultaneous perturbation stochastic approximation. Electron. Lett. 40(10), 595–597.

    Article  Google Scholar 

  • Papoulis, A. (1968) Systems and Transforms with Applications in Optics, Malabar, FL: Robert Krieger.

    Google Scholar 

  • Sheikh, R., Wang, Z., Cormack, L., and Bovik, A. (2002) Blind quality assessment for JPEG2000 compressed images. Proceedings of the IEEE Asilomar Conference on Signals Systems and Computers November 3–6, Pacific Grove, CA.

  • Simoncelli, E. and Freeman, W. (1995) The steerable pyramid: A flexible architecture for multi-scale derivative computation. Proceedings of the Second IEEE International Conference on Image Proceessing Vol. 3, pp. 444–447.

    Article  Google Scholar 

  • Sled, J. and Pike, G. (1998) Standing-wave and RF penetration artifacts caused by elliptical geometry: an electrodynamic analysis of MRI IEEE Trans. Med. Imag. 17(4), 653–662.

    Article  CAS  Google Scholar 

  • Sled, J., Zijdenbos, A., and Evans, A. (1996) A non-parametric method for automatic correction of intensity non-uniformity in MRI data. IEEE Trans. Med. Imag. 17(1), 87–97.

    Article  Google Scholar 

  • Srivastava, A., Lee, B., Simoncelli, E., and Zhu, S. (2003) On advances in statistical modeling of natural images. J. Math. Imag. Vision 18(1), 17–33.

    Article  Google Scholar 

  • Tsallis, C. (1998) Possible generalization of Boltzmann-Gibbs statistics. J. Stat. Phys. 52(1), 479–487.

    Article  Google Scholar 

  • van den Branden Lambrecht, C. (1998) (ed.) Special issue on image and video quality metrics, Signal Processing 70(3), 152–154.

    Google Scholar 

  • Wang, Z., Bovik, A., and Lu, L. (2002a) Why is image quality assessment so difficult? Proceedings of the IEEE International Conference on Acoustics Speech and Signal Processing 4, 3313–3316.

    Google Scholar 

  • Wang, Z., Sheikh, H., and Bovik, A. (2002b) No-reference perceptual quality assessment of JPEG compressed images. Proceedings of the IEEE International Conference on Image Processing, September 22–25, Rochester, NY.

  • Wang, Z. and Simoncelli, E. (2004) Local phase coherence and the perception of blur. In: Thrun, S. and Scholkopf, B. (eds.) Advances in Neural Information Processing Systems. NIPS-03, vol. 16, Cambridge, MA: MIT Press (in press).

    Google Scholar 

  • Wang, Z. and Simoncelli, E. (2005) Reduced-reference image quality assessment using a wavelet-domain natural image statistic. Proceedings of the Human Vision and Electronic Imaging, X, SPIE. 5666, Jan 17–20, 149–159.

  • Wilson, R. and Knutsson, H. (1988) Uncertainty and inference in the visual system. IEEE Trans. Syst. Man and Cybernetics 18(2), 305–312.

    Article  Google Scholar 

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Correspondence to Jeffrey P. Woodard.

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Woodard, J.P., Carley-Spencer, M.P. No-Reference image quality metrics for structural MRI. Neuroinform 4, 243–262 (2006). https://doi.org/10.1385/NI:4:3:243

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