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Measurement of Blood Plasma Amino Acids in Ultrafiltrates by High-Performance Liquid Chromatography with Automatic Precolumn O-Phthaldialdehyde Derivatization

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Amino Acid Analysis Protocols

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 159))

Abstract

Amino acid analysis is an important technique that has many applications in biochemical, pharmaceutical, and biomedical fields. Profiling of plasma amino acids is also of great interest in clinical practice. Many diseases are known to be associated with disorders in amino acid metabolism. The analysis of amino acids offers the possibility of genetic prevention in both premarital and prenatal stages for those diseases resulting from inborn errors of metabolism. The plasma amino acid pattern has been also used to follow the course of prolonged dietary treatment (1,2).

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Author information

Authors and Affiliations

  1. Department of Research, Texas Scottish Rite Hospital for Children, Dallas, TX

    Hua Liu

Authors
  1. Hua Liu
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Editor information

Editors and Affiliations

  1. Proteome Systems Ltd, North Ryde, Australia

    Catherine Cooper , Nicolle Packer  & Keith Williams ,  & 

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© 2001 Humana Press Inc.

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Liu, H. (2001). Measurement of Blood Plasma Amino Acids in Ultrafiltrates by High-Performance Liquid Chromatography with Automatic Precolumn O-Phthaldialdehyde Derivatization. In: Cooper, C., Packer, N., Williams, K. (eds) Amino Acid Analysis Protocols. Methods in Molecular Biology™, vol 159. Humana Press. https://doi.org/10.1385/1-59259-047-0:123

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  • DOI: https://doi.org/10.1385/1-59259-047-0:123

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-656-7

  • Online ISBN: 978-1-59259-047-6

  • eBook Packages: Springer Protocols

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