Following the publication of this article [1], the corresponding author contacted PLOS Genetics to indicate that it has come to their attention that the flies used in this study did not carry the patient derived PRPS mutations described in the article. The corresponding author clarified that in light of their recent findings the results and conclusions reported in this study are unreliable, and requested retraction of the article.
All authors agree with the retraction and apologize for the issues with the published article.
Reference
- 1. Delos Santos K, Kim M, Yergeau C, Jean S, Moon N-S (2019) Pleiotropic role of Drosophila phosphoribosyl pyrophosphate synthetase in autophagy and lysosome homeostasis. PLoS Genet 15(9): e1008376. https://doi.org/10.1371/journal.pgen.1008376 pmid:31487280
Citation: Santos KD, Kim M, Yergeau C, Jean S, Moon N-S (2022) Retraction: Pleiotropic role of Drosophila phosphoribosyl pyrophosphate synthetase in autophagy and lysosome homeostasis. PLoS Genet 18(2): e1010048. https://doi.org/10.1371/journal.pgen.1010048
Published: February 4, 2022
Copyright: © 2022 Santos et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.