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Correction: Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain

  • Nathanael G. Lintner,
  • Kim F. McClure,
  • Donna Petersen,
  • Allyn T. Londregan,
  • David W. Piotrowski,
  • Liuqing Wei,
  • Jun Xiao,
  • Michael Bolt,
  • Paula M. Loria,
  • Bruce Maguire,
  • Kieran F. Geoghegan,
  • Austin Huang,
  • Tim Rolph,
  • Spiros Liras,
  • Jennifer A. Doudna,
  • Robert G. Dullea,
  •  [ ... ],
  • Jamie H. D. Cate
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There is an error in reporting of the optical rotation for N-(3-chloropyridin-2-yl)-N-[(3R)-piperidin-3-yl]-4-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)benzamide (PF-06446846) in the “Synthesis of PF-06446846” subsection of the Materials and methods section. The given value of +55.9° is incorrect; the relevant passage should instead read: “[α]D25 = -55.3° (c = 1.965, MeOH).”

Reference

  1. 1. Lintner NG, McClure KF, Petersen D, Londregan AT, Piotrowski DW, Wei L, et al. (2017) Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain. PLoS Biol 15(3): e2001882. https://doi.org/10.1371/journal.pbio.2001882 pmid:28323820