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Pseudoparaproteinemia Detected by CE due to Omnipaque™ Infusion: A Case Report

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Abstract

Serum or plasma protein electrophoresis is often performed in clinical laboratories to detect and monitor M-components. During the last decade, capillary electrophoresis (CE) has emerged as an interesting alternative to traditional analysis of serum, plasma and urine proteins by agarose gel electrophoresis. We here report a case of pseudoparaproteinemia detected by capillary electrophoresis after Omnipaque™ (iohexol) infusion in a patient with normal kidney function. It is important for the laboratories to be aware of this source of erroneous results and not misclassify it as monoclonal gammopathies.

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Acknowledgements

This work was supported by the Uppsala University Hospital research fund.

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Authors and Affiliations

  1. Departments of Medical Sciences, Clinical Chemistry, University Hospital, Uppsala, Sweden

    A. Larsson & A. Lindqvist

  2. Departments of Neurosurgery, University Hospital, Uppsala, Sweden

    L. Hillered

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  1. A. Larsson
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  2. A. Lindqvist
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  3. L. Hillered
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Correspondence to A. Larsson.

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Larsson, A., Lindqvist, A. & Hillered, L. Pseudoparaproteinemia Detected by CE due to Omnipaque™ Infusion: A Case Report. Chroma 65, 775–777 (2007). https://doi.org/10.1365/s10337-007-0242-6

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  • DOI: https://doi.org/10.1365/s10337-007-0242-6

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