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Determination of Retention Factors of s-Triazines Homologous Series in Water Using a Numerical Method Basing on Ościk's Equation

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Abstract

The retention factors in pure water for a homologous series of s-triazines were calculated by a numerical method basing on Ościk's equation and were correlated with log k w values obtained by linear and parabolic extrapolation. Chromatographic data (log k w ) were compared with the software-calculated partition coefficients in the n-octanol/water system (Alog P, IAlog P, clog P, log P Kowin , xlog P, log P ACD and log P Chem.Off.) as alternative hydrophobicity indices. The effect of organic modifier (methanol and acetonitrile) and its concentration in the mobile phase used for log k w evaluation were investigated. Very good linear correlations were found between log k w values calculated by the numerical method and log P ACD , log P Chem.Off . and clog P values, independent of organic modifier type.

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Authors and Affiliations

  1. Faculty of Chemistry, Department of Physical Chemistry, Maria Curie-Skłodowska University, M. Curie-Skłodowska Sq. 3, 20-031, Lublin, Poland

    M. Janicka & L. Kwietniewski

  2. Institute of Chemistry, Faculty of Sciences, Trg Dositeja Obradovica 3, 21000, Novi Sad, Serbia and Montenegro

    N. U. Perišić-Janjić

Authors
  1. M. Janicka
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  2. L. Kwietniewski
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  3. N. U. Perišić-Janjić
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Correspondence to M. Janicka.

Additional information

Presented at: 6th Balaton Symposium on High-Performance Separation Methods, Siófok, Hungary, September 7–9, 2005

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Janicka, M., Kwietniewski, L. & Perišić-Janjić, N.U. Determination of Retention Factors of s-Triazines Homologous Series in Water Using a Numerical Method Basing on Ościk's Equation. Chroma 63 (Suppl 13), S87–S93 (2006). https://doi.org/10.1365/s10337-006-0817-7

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