Abstract
The formation of a polyelectrolyte complex between heparin (Hep) and aminoacetalized poly(vinyl alcohol) (PVAA) in aqueous media has been studied by measurements of turbidity, metachromasy, and induced circular dichroism. Three results were noted: (a) the Hep—PVAA complex in aqueous system is either in a state of liquid-solid equilibrium, or a homogeneous solution, according to the mixing conditions; (b) the reaction between Hep and PVAA was not perfectly stoichiometric; (c) the ordered structure of Hep was disordered by the formation of complex at low pH.
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Hara, M., Nakajima, A. Formation of Polyelectrolyte Complex of Heparin with Aminoacetalized Poly(vinyl alcohol). Polym J 10, 37–44 (1978). https://doi.org/10.1295/polymj.10.37
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DOI: https://doi.org/10.1295/polymj.10.37