Clinical and postmortem findings of pentalogy of Fallot in an 18-month-old Holstein heifer

Dai ISHIYAMA; Eiji MAKINO; Yoshihiro NAKAMURA; Makoto UCHIDA; Yukio ONODERA; James K. CHAMBERS; Kazuyuki UCHIDA; Fuko MATSUDA

doi:10.1292/jvms.19-0147

Internal Medicine

Clinical and postmortem findings of pentalogy of Fallot in an 18-month-old Holstein heifer

Dai ISHIYAMA, Eiji MAKINO, Yoshihiro NAKAMURA, Makoto UCHIDA, Yukio ONODERA, James K. CHAMBERS, Kazuyuki UCHIDA, Fuko MATSUDA

Author information

Dai ISHIYAMA
Sekiyado Branch Office, Western Veterinary Clinical Center, Chiba Prefectural Federated Agricultural Mutual Aid Association, 462-11 Kirigasaku, Noda-shi, Chiba 270-0213, Japan
Eiji MAKINO
Sekiyado Branch Office, Western Veterinary Clinical Center, Chiba Prefectural Federated Agricultural Mutual Aid Association, 462-11 Kirigasaku, Noda-shi, Chiba 270-0213, Japan
Yoshihiro NAKAMURA
Sekiyado Branch Office, Western Veterinary Clinical Center, Chiba Prefectural Federated Agricultural Mutual Aid Association, 462-11 Kirigasaku, Noda-shi, Chiba 270-0213, Japan
Makoto UCHIDA
Sekiyado Branch Office, Western Veterinary Clinical Center, Chiba Prefectural Federated Agricultural Mutual Aid Association, 462-11 Kirigasaku, Noda-shi, Chiba 270-0213, Japan
Yukio ONODERA
Sekiyado Branch Office, Western Veterinary Clinical Center, Chiba Prefectural Federated Agricultural Mutual Aid Association, 462-11 Kirigasaku, Noda-shi, Chiba 270-0213, Japan
James K. CHAMBERS
Department of Veterinary Medical Sciences, Graduate School of Agriculture and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan
Kazuyuki UCHIDA
Department of Veterinary Medical Sciences, Graduate School of Agriculture and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan
Fuko MATSUDA
Department of Veterinary Medical Sciences, Graduate School of Agriculture and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan

Keywords: congenital heart disease, Holstein Friesian heifer, pentalogy of Fallot, postmortem examination

JOURNAL FREE ACCESS

2019 Volume 81 Issue 11 Pages 1676-1679

DOI https://doi.org/10.1292/jvms.19-0147

Browse “Advance online publication” version

Details

Abstract

An 18-month-old female Holstein Friesian heifer presented with a history of stunted growth and a recent onset of anorexia; she presented with cyanosis and eventually died. A postmortem examination revealed obstruction of the right ventricular outflow tract, ventricular septal defect, overriding aortic root, right ventricular hypertrophy, and an atrial septal defect, indicating a pentalogy of Fallot (POF). In addition to POF, the heifer also had pulmonary artery dilatation, although she did not present with patent ductus arteriosus. This heifer had the longest lifespan among the Holstein cattle reported to have POF, which may be secondary to delayed pulmonary obstruction due to deformation of one of the pulmonary valves.

Corresponding author