Lower limb edema caused by metastatic signet ring cell stomach cancer
Dany Cruz
Internal Medicine Department at Hospital Santa Maria Maior, Portugal |
Catarina Pinto Silva
Internal Medicine, Department at Hospital Santa Maria Maior, Portugal |
Cristina Marques
Internal Medicine, Department at Hospital Santa Maria Maior, Portugal |
Francisca Pereira
Internal Medicine, Department at Hospital Santa Maria Maior, Portugal |
Alexandra Leitão
Internal Medicine, Department at Hospital Santa Maria Maior, Portugal |
Ana Ogando
Internal Medicine, Department at Hospital Santa Maria Maior, Portugal |
Keywords
Signet Ring Cell Carcinoma, Gastric cancer, Paraneoplasic syndrome
Abstract
Overall gastric cancer incidence is decreasing, but incidence of gastric signet ring cell carcinoma has been rising. The diagnosis can be challenging. It has a poorer prognosis because it tends to be diagnosed at advanced stages. Lymphedema is a rare presentation. We report a rare presentation of signet ring cell carcinoma in a 49-year old male, with no underlying medical condition. The patient presented with lymphedema of lower limbs, scrotum and abdominal wall.
References
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- Taghavi S, Jayarajan SN, Davey A, Willis AI. Prognostic significance of Signet Ring Gastric Cancer. Journal of Clinical Oncology. 2012;30:3493–8.
- Raval N, Shmuylovich L, Strickley J, Chen TY, Rosman IS, Musiek A. Signet-ring cutaneous metastasis presenting with massive anasarca. JAAD Case Reports. 2021;10:123–5.
- da Souza B, Bonamigo RR, Viapiana GL, Cartell A. Signet ring cells in carcinomatous lymphangitis due to gastric adenocarcinoma. Anais Brasileiros de Dermatologia. 2020;95:490–2. doi:10.1016/j.abd.2019.12.004

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Published:
2023-08-07
Issue:
Vol. 10 No. 9 (2023)
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