Journal of Nippon Medical School
Online ISSN : 1347-3409
Print ISSN : 1345-4676
ISSN-L : 1345-4676
Early and post-treatment imaging findings in perineural spread: a pathway to diffuse muscle metastasis in recurrent bladder carcinoma
Yoshimitsu Honda, Tetsuro Sekine, Ryoji Kimata, Norio Motoda, Keigo Takahashi, Aya Yamane, Daisuke Yasui, Eigo Kodani, Taro Ichikawa, Shinichiro Kumita
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Keywords: muscle metastasis, bladder carcinoma, perineural spread, PET/CT, MRI
JOURNAL FREE ACCESS Advance online publication

Article ID: JNMS.2024_91-301

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Abstract

Perineural spread (PNS) from pelvic carcinoma has been regarded as a pathway to muscle and bone metastasis. However, few cases have been reported, especially in patients with bladder carcinoma. In the present report, we discuss a case of diffuse cancer involvement in the muscle 5 years after radical cystectomy for advanced bladder carcinoma. Careful observation of temporal changes on medical images confirmed PNS as the pathway to muscle metastasis (i.e., primary PNS). Our report presents early and post-treatment CT, MRI and FDG-PET/CT findings of PNS from the bladder carcinoma.

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