[1]
|
Mendez-Ferrer, S., Bonnet, D., Steensma, D.P., et al. (2020) Bone Marrow Niches in Haematological Malignancies. Nature Reviews Cancer, 20, 285-298. https://doi.org/10.1038/s41568-020-0245-2
|
[2]
|
Zhong, J., Wu, H., Bu, X., et al. (2021) Establishment of Prognosis Model in Acute Myeloid Leukemia Based on Hypoxia Microenvironment, and Exploration of Hypoxia-Related Mechanisms. Frontiers in Genetics, 12, Article 727392.
https://doi.org/10.3389/fgene.2021.727392
|
[3]
|
Godet, I., Shin, Y.J., Ju, J.A., et al. (2019) Fate-Mapping Post-Hypoxic Tumor Cells Reveals a ROS-Resistant Phenotype That Promotes Metastasis. Nature Communications, 10, Article No. 4862.
https://doi.org/10.1038/s41467-019-12412-1
|
[4]
|
Sendker, S., Waack, K. and Reinhardt, D. (2021) Far from Health: The Bone Marrow Microenvironment in AML, A Leukemia Supportive Shelter. Children (Basel), 8, Article 371. https://doi.org/10.3390/children8050371
|
[5]
|
Kuek, V., Hughes, A.M., Kotecha, R.S. and Cheung, L.C. (2021) Therapeutic Targeting of the Leukaemia Microenvironment. International Journal of Molecular Sciences, 22, Article 6888. https://doi.org/10.3390/ijms22136888
|
[6]
|
Bruno, S., Mancini, M., De Santis, S., et al. (2021) The Role of Hypoxic Bone Marrow Microenvironment in Acute Myeloid Leukemia and Future Therapeutic Opportunities. Interna-tional Journal of Molecular Sciences, 22, Article 6857. https://doi.org/10.3390/ijms22136857
|
[7]
|
Kaweme, N.M. and Zhou, F. (2021) Optimizing NK Cell-Based Immunotherapy in Myeloid Leukemia: Abrogating an Immunosuppres-sive Microenvironment. Frontiers in Immunology, 12, Article 683381.
https://doi.org/10.3389/fimmu.2021.683381
|
[8]
|
Pinho, S. and Frenette, P.S. (2019) Haematopoietic Stem Cell Ac-tivity and Interactions with the Niche. Nature Reviews Molecular Cell Biology, 20, 303-320. https://doi.org/10.1038/s41580-019-0103-9
|
[9]
|
Gomes, A.C., Saraiva, M. and Gomes, M.S. (2021) The Bone Marrow Hematopoietic Niche and Its Adaptation to Infection. Seminars in Cell & Developmental Biology, 112, 37-48. https://doi.org/10.1016/j.semcdb.2020.05.014
|
[10]
|
Bapat, A., Schippel, N., Shi, X., et al. (2021) Hypoxia Pro-motes Erythroid Differentiation through the Development of Progenitors and Proerythroblasts. Experimental Hematology, 97, 32-46. https://doi.org/10.1016/j.exphem.2021.02.012
|
[11]
|
Shalapour, S. and Karin, M. (2019) Pas de Deux: Control of Anti-Tumor Immunity by Cancer-Associated Inflammation. Immunity, 51, 15-26. https://doi.org/10.1016/j.immuni.2019.06.021
|
[12]
|
Li, L., Zhao, L., Man, J. and Liu, B. (2021) CXCL2 Benefits Acute Myeloid Leukemia Cells in Hypoxia. International Journal of Laboratory Hematology, 43, 1085-1092. https://doi.org/10.1111/ijlh.13512
|
[13]
|
Ciciarello, M., Corradi, G., Forte, D., Cavo, M. and Curti, A. (2021) Emerging Bone Marrow Microenvironment-Driven Mechanisms of Drug Resistance in Acute Myeloid Leukemia: Tangle or Chance? Cancers, 13, Article 5319. https://doi.org/10.3390/cancers13215319
|
[14]
|
Tommasini-Ghelfi, S., Murnan, K., Kouri, F.M., et al. (2019) Cancer-Associated Mutation and Beyond: The Emerging Biology of Isocitrate Dehydrogenases in Human Disease. Science Advances, 5, eaaw4543.
https://doi.org/10.1126/sciadv.aaw4543
|
[15]
|
Fernandes, M.T., Calado, S.M., Mendes-Silva, L. and Bragança, J. (2020) CITED2 and the Modulation of the Hypoxic Response in Cancer. World Journal of Clinical Oncology, 11, 260-274. https://doi.org/10.5306/wjco.v11.i5.260
|
[16]
|
Rashid, M., Zadeh, L.R., Baradaran, B., et al. (2021) Up-Down Regulation of HIF-1α in Cancer Progression. Gene, 798, Article ID: 145796. https://doi.org/10.1016/j.gene.2021.145796
|
[17]
|
Zhu, G., Wang, L., Meng, W., et al. (2021) LOXL2-Enriched Small Extracellular Vesicles Mediate Hypoxia-Induced Premetastatic Niche and Indicates Poor Outcome of Head and Neck Cancer. Theranostics, 11, 9198-9216.
https://doi.org/10.7150/thno.62455
|
[18]
|
Li, X., Yang, Y., Zhang, B., et al. (2022) Lactate Metabolism in Human Health and Disease. Signal Transduction and Targeted Therapy, 7, Article No. 305. https://doi.org/10.1038/s41392-022-01151-3
|
[19]
|
Martinez-Outschoorn, U.E., Peiris-Pages, M., Pestell, R.G., Sot-gia, F. and Lisanti, M.P. (2017) Cancer Metabolism: A Therapeutic Perspective. Nature Reviews Clinical Oncology, 14, 11-31. https://doi.org/10.1038/nrclinonc.2016.60
|
[20]
|
马苑, 付秀华, 王立红. 肿瘤缺氧微环境的研究进展[J]. 癌症进展, 2020, 18(2): 109-112, 147.
|
[21]
|
周程继, 贾家猛, 王贤芝, 等. 缺氧微环境与胃肠道肿瘤转移的关系研究进展[J]. 西部医学, 2017, 29(9): 1328-1331.
|
[22]
|
侯艳, 李文倩, 冯建明, 等. 低氧诱导因子-1α参与慢性粒细胞白血病发病机制的研究进展[J]. 国际免疫学杂志, 2018, 41(5): 578-581.
|
[23]
|
Karagiota, A., Kourti, M., Simos, G. and Mylonis, I. (2019) HIF-1α-Derived Cell-Penetrating Peptides Inhibit ERK-Dependent Activation of HIF-1 and Trig-ger Apoptosis of Cancer Cells under Hypoxia. Cellular and Molecular Life Sciences, 76, 809-825. https://doi.org/10.1007/s00018-018-2985-7
|
[24]
|
刘文静, 李大启. 缺氧骨髓微环境在急性髓细胞白血病中的研究现状[J]. 国际输血及血液学杂志, 2022, 45(4): 284-289.
|
[25]
|
Takubo, K., Goda, N., Yamada, W., et al. (2010) Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells. Cell Stem Cell, 7, 391-402. https://doi.org/10.1016/j.stem.2010.06.020
|
[26]
|
Wang, Y., Liu, Y., Malek, S.N., Zheng, P. and Liu, Y. (2011) Targeting HIF1α Eliminates Cancer Stem Cells in Hematological Malignancies. Cell Stem Cell, 8, 399-411. https://doi.org/10.1016/j.stem.2011.02.006
|
[27]
|
Wang, Y., Liu, Y., Bailey, C., et al. (2020) Therapeutic Targeting of TP53-Mutated Acute Myeloid Leukemia by Inhibiting HIF-1α with Echinomycin. Oncogene, 39, 3015-3027. https://doi.org/10.1038/s41388-020-1201-z
|
[28]
|
Hoseinkhani, Z., Rastegari-Pouyani, M., Oubari, F., et al. (2019) Contribution and Prognostic Value of TSGA10 Gene Expression in Patients with Acute Myeloid Leukemia (AML). Pa-thology—Research and Practice, 215, 506-511.
https://doi.org/10.1016/j.prp.2019.01.003
|
[29]
|
Sharma, M., Ross, C. and Srivastava, S. (2019) Ally to Adversary: Mesenchymal Stem Cells and Their Transformation in Leukaemia. Cancer Cell International, 19, Article No. 139. https://doi.org/10.1186/s12935-019-0855-5
|
[30]
|
Kong, F., He, H., Bai, H., et al. (2022) A Biomimetic Nanocom-posite with Enzyme-Like Activities and CXCR4 Antagonism Efficiently Enhances the Therapeutic Efficacy of Acute Myeloid Leukemia. Bioactive Materials, 18, 526-538.
https://doi.org/10.1016/j.bioactmat.2022.03.022
|
[31]
|
Tang, W., Li, Z., Li, X. and Huo, Z.H. (2020) High CXCR2 Expression Predicts Poor Prognosis in Adult Patients with Acute Myeloid Leukemia. Therapeutic Advances in Hema-tology, 11, 1-13.
https://doi.org/10.1177/2040620720958586
|
[32]
|
Min, Q., Feng, S.L., Lu, H., et al. (2019) Modulation of Drug-Metabolizing Enzymes and Transporters under Hypoxia Environment. Acta Physiologica Sinica, 71, 336-342.
|
[33]
|
Alonso, S., Su, M., Jones, J.W., et al. (2015) Human Bone Marrow Niche Chemoprotection Mediated by Cytochrome P450 Enzymes. Oncotarget, 6, 14905-14912. https://doi.org/10.18632/oncotarget.3614
|
[34]
|
Li, X., Su, Y., Madlambayan, G., et al. (2019) Antileukemic Activity and Mechanism of Action of the Novel PI3K and Histone Deacetylase Dual Inhibitor CUDC-907 in Acute Myeloid Leukemia. Haematologica, 104, 2225-2240.
https://doi.org/10.3324/haematol.2018.201343
|
[35]
|
Watanabe, D., Nogami, A., Okada, K., et al. (2019) FLT3-ITD Activates RSK1 to Enhance Proliferation and Survival of AML Cells by Activating mTORC1 and eIF4B Cooperatively with PIM or PI3K and by Inhibiting Bad and BIM. Cancers, 11, Article 1827. https://doi.org/10.3390/cancers11121827
|
[36]
|
Hira, V., Van Noorden, C., Carraway, H.E., Maciejewski, J.P. and Molenaar, R.J. (2017) Novel Therapeutic Strategies to Target Leukemic Cells That Hijack Compartmentalized Continuous Hematopoietic Stem Cell Niches. Biochimica et Biophysica Acta—Reviews on Cancer, 1868, 183-198. https://doi.org/10.1016/j.bbcan.2017.03.010
|