31 May 2019 : Original article
Evolution of Indications for Liver Transplantation (LTx) in the Years 2001–2017 in Poland
Paweł Koczkodaj12ABCDEF, Wojciech Straś3BCD, Jarosław Czerwiński45BCDE, Piotr Małkowski6ABCD, Mariusz Panczyk1CD, Joanna Gotlib1ADEFDOI: 10.12659/AOT.915958
Ann Transplant 2019; 24:312-318
Abstract
BACKGROUND: Hepatitis B and C viruses have been recognized as undoubtedly carcinogenic to humans. In the Polish population, where most people are protected by HBV vaccinations, hepatocellular carcinoma (HCC) and its main cause, persistent HCV infection, significantly affect the demand for liver transplantations.
MATERIAL AND METHODS: The purpose of this study was to categorize the number of primary liver transplantations in Poland in the years 2001–2017 by cause and to analyze changes in LTx indications during this period. Data were sourced from POLTRANSPLANT, the Organization and Coordination Center for Transplantation in Poland. Additionally, we compared the numbers of HCC cases and hepatitis B and C cases during this period.
RESULTS: In the analyzed period, in Poland, 3332 primary liver transplantations were performed. Overall, 44% (1456) of LTx cases were combined with HBV and/or HCV and/or HCC. In this group, transplants in patients with only 1 specific factor – HCV – formed the largest cohort, accounting for about 40% (581) of cases. Transplants in patients who only had HBV and in those who only had HCC accounted for 12% (185) and 5% (69), respectively.
CONCLUSIONS: The analyzed data suggest that HCV infections are a significant public health problem in Poland, as is also reflected by the growing number of LTx performed due to HCC. To limit the numbers of HCV and HCC cases, immediate implementation of a Polish National Program against HCV should be considered.
Keywords: Carcinoma, Hepatocellular, Hepatitis B, Hepatitis C, Liver Transplantation, Poland, Public Health, Adolescent, Aged, 80 and over, Liver Neoplasms, Risk Factors, young adult
In Press
Original article
Physical Activity Levels in Transplant RecipientsAnn Transplant In Press; DOI: 10.12659/AOT.944101
Original article
Implementation and Evaluation of Discharge Planning for Patients Undergoing Umbilical Cord Blood Transplant...Ann Transplant In Press; DOI: 10.12659/AOT.943770
Original article
Long-Term Graft and Patient Survival After Re-TransplantationAnn Transplant In Press; DOI: 10.12659/AOT.943903
Original article
Post-Donation Regret and Anxiety Among Family Living Liver Donors: The Mediating Roles of Family Relationsh...Ann Transplant In Press; DOI: 10.12659/AOT.944176
Most Viewed Current Articles
05 Apr 2022 : Original article
Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver TransplantationDOI :10.12659/AOT.935604
Ann Transplant 2022; 27:e935604
12 Jan 2022 : Original article
Risk Factors for Developing BK Virus-Associated Nephropathy: A Single-Center Retrospective Cohort Study of ...DOI :10.12659/AOT.934738
Ann Transplant 2022; 27:e934738
22 Nov 2022 : Original article
Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...DOI :10.12659/AOT.937988
Ann Transplant 2022; 27:e937988
15 Mar 2022 : Case report
Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...DOI :10.12659/AOT.935860
Ann Transplant 2022; 27:e935860